| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4774626 | B | Inhibition of factor 2a (unknown origin) at IC50 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 2. | ALA4774627 | B | Inhibition of factor 7a (unknown origin) at IC50 using pefachrome factor VIIa as substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 3. | ALA4774628 | B | Inhibition of factor 10a (unknown origin) at IC50 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 4. | ALA4774629 | B | Inhibition of factor 11a (unknown origin) at IC50 using S-2366 as substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 5. | ALA4774630 | B | Inhibition of factor 12a (unknown origin) at IC50 using kallikrein chromogenic substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 6. | ALA4774631 | B | Inhibition of factor 2a (unknown origin) at IC50 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 7. | ALA4774632 | B | Inhibition of factor 7a (unknown origin) at IC50 using pefachrome factor VIIa as substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 8. | ALA4774633 | B | Inhibition of factor 10a (unknown origin) at IC50 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 9. | ALA4774634 | B | Inhibition of factor 11a (unknown origin) at IC50 using S-2366 as substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 10. | ALA4774635 | B | Inhibition of factor 12a (unknown origin) at IC50 using kallikrein chromogenic substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 11. | ALA4774636 | B | Inhibition of factor 2a (unknown origin) at IC90 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 12. | ALA4774637 | B | Inhibition of factor 11a (unknown origin) at IC90 using S-2366 as substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 13. | ALA4774638 | A | Inhibition of factor 12a (unknown origin) at IC90 using kallikrein chromogenic substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 14. | ALA4774639 | B | Inhibition of factor 10a (unknown origin) at IC90 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III relative to control | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 15. | ALA4774672 | F | Anticoagulation activity in human plasma assessed as drug level causing 20 times doubling of APTT preincubated for 2 mins followed by APTT reagent and measured after 3 mins by coagulometric method relative to dHG-5 | Homo sapiens | 9 | cell-free format | Scientific Literature | ||
| 16. | ALA4774673 | B | Inhibition of human citrated plasma iXase (factor 8a-factor 9a complex) preincubated for 2 mins followed by factor 10 addition and measured after 1 min by FXa chromogenic substrate SXa-11 based assay relative to dHG-5 | Homo sapiens | 9 | protein complex format | Scientific Literature | ||
| 17. | ALA4774674 | B | Inhibition of factor 9a (unknown origin) binding to immobilized biotinylated oHG-11 by biolayer interferometry relative to dHG-5 | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 18. | ALA4774681 | F | Antithrombotic activity in thromboplastin and stasis-induced Sprague-Dawley rat deep venous thrombosis model assessed as reduction in venous thrombosis at 1.66 mg/kg, sc administered 1 hr prior to thromboplastin addition for 20 secs followed by establishment of stasis for 20 mins relative to dHG-5 | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4774683 | F | Anticoagulation activity in human plasma assessed as drug level causing 20 times doubling of APTT by measuring activity potency of oligosaccharides multiplied by the percentage of oligosaccharides in dHG-5 preincubated for 2 mins followed by APTT reagent and measured after 3 mins by coagulometric method relative to dHG-5 | Homo sapiens | 9 | cell-free format | Scientific Literature | ||
| 20. | ALA4774684 | B | Inhibition of human citrated plasma iXase (factor 8a-factor 9a complex) assessed as activity potency of oligosaccharides multiplied by the percentage of oligosaccharides in dHG-5 preincubated for 2 mins followed by factor 10 addition and measured after 1 min by FXa chromogenic substrate SXa-11 based assay relative to dHG-5 | Homo sapiens | 9 | protein complex format | Scientific Literature |
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