# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4767283 | Functional | Antiproliferative activity against human KMS-11 cells assessed as reduction in cell viability at 0.1 to 100 uM incubated for 48 hrs by cell-titer-Glo luminescent cell viability assay | Homo sapiens | 4 | ALA4765242 | cell-based format | Scientific Literature | |
2. | ALA4767284 | Functional | Antiproliferative activity against human KOPN-8 cells assessed as reduction in cell viability at 0.1 to 100 uM incubated for 48 hrs by cell-titer-Glo luminescent cell viability assay | Homo sapiens | 2 | ALA4765242 | cell-based format | Scientific Literature | |
3. | ALA4767285 | Functional | Antiproliferative activity against human HL-60 cells assessed as reduction in cell viability at 0.1 to 100 uM incubated for 48 hrs by cell-titer-Glo luminescent cell viability assay | Homo sapiens | 2 | ALA4765242 | cell-based format | Scientific Literature | |
4. | ALA4767286 | Functional | Antiproliferative activity against human KG-1a cells assessed as reduction in cell viability at 0.1 to 100 uM incubated for 48 hrs by cell-titer-Glo luminescent cell viability assay | Homo sapiens | 4 | ALA4765242 | cell-based format | Scientific Literature | |
5. | ALA4767287 | Functional | Antiproliferative activity against human A549 cells assessed as reduction in cell viability at 0.1 to 100 uM incubated for 48 hrs by cell-titer-Glo luminescent cell viability assay | Homo sapiens | 4 | ALA4765242 | cell-based format | Scientific Literature | |
6. | ALA4767288 | Functional | Antiproliferative activity against human HeLa cells assessed as reduction in cell viability at 0.1 to 100 uM incubated for 48 hrs by cell-titer-Glo luminescent cell viability assay | Homo sapiens | 4 | ALA4765242 | cell-based format | Scientific Literature | |
7. | ALA4767289 | Functional | Antiproliferative activity against human SEM cells assessed as reduction in cell viability at 0.1 to 100 uM incubated for 48 hrs by cell-titer-Glo luminescent cell viability assay | Homo sapiens | 2 | ALA4765242 | cell-based format | Scientific Literature | |
8. | ALA4767290 | Functional | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability at 0.1 to 100 uM incubated for 48 hrs by cell-titer-Glo luminescent cell viability assay | Homo sapiens | 2 | ALA4765242 | cell-based format | Scientific Literature | |
9. | ALA4767291 | Functional | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 48 hrs by cell-titer-Glo luminescent cell viability assay | Homo sapiens | 18 | ALA4765242 | cell-based format | Scientific Literature | |
10. | ALA4767292 | ADME | Cytotoxicity against HUVEC assessed as reduction in cell viability incubated for 48 hrs by cell-titer-Glo luminescent cell viability assay | Homo sapiens | 18 | ALA4765242 | cell-based format | Scientific Literature | |
11. | ALA4767293 | Toxicity | Selectivity index, ratio of IC50 for HUVEC to IC50 for human MV4-11 cells | 18 | ALA4765242 | assay format | Scientific Literature | ||
12. | ALA4767294 | ADME | Half life in mouse liver microsomes at 10 uM preincubated for 5 mins followed by NADPH addition and measured up to 45 mins by LC/MS analysis | Mus musculus | 6 | ALA4765242 | microsome format | Scientific Literature | |
13. | ALA4767295 | ADME | Intrinsic clearance mouse in liver microsomes at 10 uM preincubated for 5 mins followed by NADPH addition and measured up to 45 mins by LC/MS analysis | Mus musculus | 6 | ALA4765242 | subcellular format | Scientific Literature |