# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4704712 | Binding | Agonist activity at human FFA4 receptor expressed in CHO-K1 cells assessed as increase in amplitude of dynamic mass redistribution response by DMR assay | Homo sapiens | 25 | ALA4699604 | cell-based format | Scientific Literature | |
2. | ALA4704713 | Binding | Agonist activity at human FFA4 receptor expressed in CHO-K1 cells assessed as efficacy of increase in amplitude of dynamic mass redistribution response by DMR assay relative to control | Homo sapiens | 21 | ALA4699604 | cell-based format | Scientific Literature | |
3. | ALA4704714 | Binding | Agonist activity at human FFA1 receptor expressed in CHO-K1 cells assessed as increase in dynamic mass redistribution response by DMR assay | Homo sapiens | 25 | ALA4699604 | cell-based format | Scientific Literature | |
4. | ALA4704715 | Binding | Selectivity index, ratio of EC50 for agonist activity at human FFA1 receptor expressed in CHO-K1 cells to EC50 for agonist activity at human FFA4 receptor expressed in CHO-K1 cells by DMR assay | Homo sapiens | 21 | ALA4699604 | cell-based format | Scientific Literature | |
5. | ALA4704716 | Binding | Agonist activity at M1 receptor (unknown origin) assessed as reduction in dynamic mass redistribution response of corresponding probe at 20 uM by DMR desensitization assay | Homo sapiens | 1 | ALA4699604 | single protein format | Scientific Literature | |
6. | ALA4704717 | Binding | Agonist activity at mu opioid receptor (unknown origin) assessed as reduction in dynamic mass redistribution response of corresponding probe at 20 uM by DMR desensitization assay | Homo sapiens | 1 | ALA4699604 | single protein format | Scientific Literature | |
7. | ALA4704718 | Binding | Agonist activity at H2 receptor (unknown origin) assessed as reduction in dynamic mass redistribution response of corresponding probe at 20 uM by DMR desensitization assay | Homo sapiens | 1 | ALA4699604 | single protein format | Scientific Literature | |
8. | ALA4704719 | Binding | Agonist activity at beta2 receptor (unknown origin) assessed as reduction in dynamic mass redistribution response of corresponding probe at 40 uM by DMR desensitization assay | Homo sapiens | 1 | ALA4699604 | single protein format | Scientific Literature | |
9. | ALA4704720 | Binding | Agonist activity at GPR35 receptor (unknown origin) assessed as reduction in dynamic mass redistribution response of corresponding probe at 40 uM by DMR desensitization assay | Homo sapiens | 1 | ALA4699604 | single protein format | Scientific Literature | |
10. | ALA4704721 | Binding | Agonist activity at ETA receptor (unknown origin) assessed as reduction in dynamic mass redistribution response of corresponding probe at 20 uM by DMR desensitization assay | Homo sapiens | 1 | ALA4699604 | single protein format | Scientific Literature | |
11. | ALA4704722 | Binding | Agonist activity at ETB receptor (unknown origin) assessed as reduction in dynamic mass redistribution response of corresponding probe at 20 uM by DMR desensitization assay | Homo sapiens | 1 | ALA4699604 | single protein format | Scientific Literature | |
12. | ALA4704723 | Functional | Antidiabetic activity in db/db mouse assessed as reduction in plasma glucose AUC at 10 mg/kg, ip administered prior to glucose challenge and measured after 1 hr by OGTT relative to control | Mus musculus | 2 | ALA4699604 | organism-based format | Scientific Literature | |
13. | ALA4704724 | Functional | Antidiabetic activity in db/db mouse assessed as reduction in plasma glucose AUC at 20 mg/kg, ip administered prior to glucose challenge and measured after 1 hr by OGTT relative to control | Mus musculus | 1 | ALA4699604 | organism-based format | Scientific Literature | |
14. | ALA4704727 | Binding | Selectivity for human FFA4 receptor expressed in CHO-K1 cells over GPR35 receptor (unknown origin) at 40 uM | Homo sapiens | 1 | ALA4699604 | cell-based format | Scientific Literature | |
15. | ALA4704728 | Binding | Selectivity for human FFA4 receptor expressed in CHO-K1 cells over beta2 receptor (unknown origin) at 40 uM | Homo sapiens | 1 | ALA4699604 | cell-based format | Scientific Literature | |
16. | ALA4704729 | Binding | Selectivity for human FFA4 receptor expressed in CHO-K1 cells over H2 receptor (unknown origin) at 20 uM | Homo sapiens | 1 | ALA4699604 | cell-based format | Scientific Literature | |
17. | ALA4704730 | Binding | Selectivity for human FFA4 receptor expressed in CHO-K1 cells over ET-B receptor (unknown origin) at 20 uM | Homo sapiens | 1 | ALA4699604 | cell-based format | Scientific Literature | |
18. | ALA4704731 | Binding | Selectivity for human FFA4 receptor expressed in CHO-K1 cells over ET-A receptor (unknown origin) at 20 uM | Homo sapiens | 1 | ALA4699604 | cell-based format | Scientific Literature | |
19. | ALA4704732 | Binding | Selectivity for human FFA4 receptor expressed in CHO-K1 cells over mu opioid receptor (unknown origin) at 20 uM | Homo sapiens | 1 | ALA4699604 | cell-based format | Scientific Literature | |
20. | ALA4704733 | Binding | Selectivity for human FFA4 receptor expressed in CHO-K1 cells over M1 receptor (unknown origin) at 20 uM | Homo sapiens | 1 | ALA4699604 | cell-based format | Scientific Literature |