#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4669200	Binding	Potency index, ratio of (R)-MB001 EC50 to test compound EC50 for inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated with enzyme for 5 mins followed by further incubation with all-trans-retinol for 1 hr by normal phase HPLC analysis	Bos taurus	2	ALA4665714	microsome format	Scientific Literature
2.	ALA4669201	Binding	Inhibition of RPE65 in bovine RPE microsomes assessed as reduction in 11-cis-retinol production using all-trans-retinol as substrate pre-incubated with enzyme for 5 mins followed by further incubation with all-trans-retinol for 1 hr by normal phase HPLC analysis	Bos taurus	3	ALA4665714	microsome format	Scientific Literature
3.	ALA4669202	Functional	Cytoprotective activity against human ARPE-19 cells assessed as reduction in all-trans-retinal induced cytotoxicity at 18 to 90 uM incubated for 6 hrs in presence of all-trans-retinal by CellTiter-Glo luminescent cell viability assay	Homo sapiens	3	ALA4665714	cell-based format	Scientific Literature
4.	ALA4669203	Functional	Cytoprotective activity against human ARPE-19 cells assessed as reduction in all-trans-retinal induced cytotoxicity by measuring cell surveillance rate at 90 uM incubated for 6 hrs in presence of all-trans-retinal by CellTiter-Glo luminescent cell viability assay relative to control	Homo sapiens	1	ALA4665714	cell-based format	Scientific Literature