# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4765504 | B | Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene-based spectrophotometric method | Homo sapiens | 40 | ALA4765226 | cell-based format | Scientific Literature | |
2. | ALA4765505 | B | Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by measuring maximal response by quanti-blue SEAP reporter gene-based spectrophotometric method | Homo sapiens | 41 | ALA4765226 | cell-based format | Scientific Literature | |
3. | ALA4765518 | B | Agonist activity at human TLR2 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method | Homo sapiens | 43 | ALA4765226 | cell-based format | Scientific Literature | |
4. | ALA4765519 | B | Agonist activity at human TLR3 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method | Homo sapiens | 43 | ALA4765226 | cell-based format | Scientific Literature | |
5. | ALA4765520 | B | Agonist activity at human TLR4 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method | Homo sapiens | 43 | ALA4765226 | cell-based format | Scientific Literature | |
6. | ALA4765521 | B | Agonist activity at human TLR5 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method | Homo sapiens | 43 | ALA4765226 | cell-based format | Scientific Literature | |
7. | ALA4765522 | B | Agonist activity at human TLR7 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method | Homo sapiens | 43 | ALA4765226 | cell-based format | Scientific Literature | |
8. | ALA4765523 | B | Agonist activity at human TLR9 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB activation by quanti-blue SEAP reporter gene based spectrophotometric method | Homo sapiens | 43 | ALA4765226 | cell-based format | Scientific Literature |