| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4714360 | B | Inhibition of tyrosinase in mouse B16F10 cells assessed melanin level at 8 uM after 24 hrs relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4714362 | B | Inhibition of mushroom tyrosinase using L-DOPA as substrate at 10 uM preincubated for 20 mins followed by substrate addition and measured after 10 mins relative to control | Agaricus bisporus | 15 | assay format | Scientific Literature | ||
| 3. | ALA4714363 | B | Inhibition of mushroom tyrosinase using L-DOPA as substrate at 0.5 uM preincubated for 20 mins followed by substrate addition and measured after 10 mins relative to control | Agaricus bisporus | 15 | assay format | Scientific Literature | ||
| 4. | ALA4714364 | B | Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 20 mins followed by substrate addition and measured after 10 mins | Agaricus bisporus | 16 | assay format | Scientific Literature | ||
| 5. | ALA4714365 | F | Antioxidant activity assessed as inhibition of DPPH radical activity at 100 uM incubated for 20 mins by spectrophotometric method relative to control | 16 | assay format | Scientific Literature | |||
| 6. | ALA4714366 | B | Uncompetitive inhibition of mushroom tyrosinase assessed as Km at 0.5 uM using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by Lineweaver-Burk plot analysis (Rvb = 37.31 uM) | Agaricus bisporus | 1 | assay format | Scientific Literature | ||
| 7. | ALA4714367 | B | Uncompetitive inhibition of mushroom tyrosinase assessed as Km at 2.5 uM using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by Lineweaver-Burk plot analysis (Rvb = 37.31 uM) | Agaricus bisporus | 1 | assay format | Scientific Literature | ||
| 8. | ALA4714368 | B | Uncompetitive inhibition of mushroom tyrosinase assessed as Km at 10 uM using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by Lineweaver-Burk plot analysis (Rvb = 37.31 uM) | Agaricus bisporus | 1 | assay format | Scientific Literature | ||
| 9. | ALA4714369 | B | Uncompetitive inhibition of mushroom tyrosinase assessed as Vmax at 0.5 uM using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by Lineweaver-Burk plot analysis (Rvb = 8.92 OD/min) | Agaricus bisporus | 1 | assay format | Scientific Literature | ||
| 10. | ALA4714370 | B | Uncompetitive inhibition of mushroom tyrosinase assessed as Vmax at 2.5 uM using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by Lineweaver-Burk plot analysis (Rvb = 8.92 OD/min) | Agaricus bisporus | 1 | assay format | Scientific Literature | ||
| 11. | ALA4714371 | B | Uncompetitive inhibition of mushroom tyrosinase assessed as Vmax at 10 uM using L-DOPA as substrate preincubated for 10 mins followed by substrate addition and measured after 10 mins by Lineweaver-Burk plot analysis (Rvb = 8.92 OD/min) | Agaricus bisporus | 1 | assay format | Scientific Literature | ||
| 12. | ALA4714372 | B | Inhibition of tyrosinase in mouse B16F10 cells assessed reduction in melanin level at 2 uM after 24 hrs | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4714373 | A | Cytotoxicity against mouse B16F10 cells assessed as reduction in cell viability at 2 to 4 uM after 48 hrs by MTT assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4714374 | A | Cytotoxicity against mouse B16F10 cells assessed as reduction in cell viability at 8 uM after 48 hrs by MTT assay | Mus musculus | 2 | cell-based format | Scientific Literature |
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