| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4738086 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 2. | ALA4738087 | F | Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 3. | ALA4738088 | F | Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA4738089 | F | Cytotoxicity against human DLD-1 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 5. | ALA4738090 | F | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 6. | ALA4738091 | B | Inhibition of HDAC1 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 7. | ALA4738092 | B | Inhibition of HDAC2 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 8. | ALA4738094 | B | Inhibition of HDAC8 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 9. | ALA4738096 | F | Antiproliferative activity against HDACi-sensitive human YCC-11 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 3 | tissue-based format | Scientific Literature | ||
| 10. | ALA4738097 | F | Antiproliferative activity against HDACi-resistant human YCC3/7 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 3 | tissue-based format | Scientific Literature | ||
| 11. | ALA4738099 | F | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as sub-G1 phase at 4 uM incubated for 72 hrs by PI staining based flow cytometry analysis (Rvb = 0.8 %) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4738100 | F | Induction of cell cycle arrest in human MDA-MB-231 cells assessed as sub-G1 phase at 8 uM incubated for 72 hrs by PI staining based flow cytometry analysis (Rvb = 0.8 %) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA4738101 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as increase in activated caspase-3 at 4 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4738102 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as increase in activated caspase-9 at 4 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4738103 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as decrease in MCL-1 at 4 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4738104 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as decrease in Bcl-xl at 4 uM incubated for 72 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4738105 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as viable cells at 4 uM incubated for 72 hrs by annexin-V-FITC and PI staining based flow cytometry analysis (Rvb = 93.4 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4738106 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as early apoptotic cells at 4 uM incubated for 72 hrs by annexin-V-FITC and PI staining based flow cytometry analysis (Rvb = 1.1 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4738107 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as late apoptotic cells at 4 uM incubated for 72 hrs by annexin-V-FITC and PI staining based flow cytometry analysis (Rvb = 2.7 %) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4738108 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as necrotic cells at 4 uM incubated for 72 hrs by annexin-V-FITC and PI staining based flow cytometry analysis (Rvb = 2.8 %) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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