# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4669625 | Functional | Induction of apoptosis in human HelaM cells assessed as increase in caspase-9 level at 10 uM incubated for 24 hrs | Homo sapiens | 1 | ALA4665747 | cell-based format | Scientific Literature | |
2. | ALA4669626 | Functional | Induction of apoptosis in human HelaM cells assessed as increase in p53 level at 10 uM incubated for 24 hrs | Homo sapiens | 1 | ALA4665747 | cell-based format | Scientific Literature | |
3. | ALA4669627 | Functional | Induction of apoptosis in human HelaM cells assessed as increase in caspase-8 level at 10 uM incubated for 24 hrs | Homo sapiens | 1 | ALA4665747 | cell-based format | Scientific Literature | |
4. | ALA4669628 | Functional | Induction of apoptosis in human HelaM cells assessed as increase in Bcl2 level at 10 uM incubated for 24 hrs | Homo sapiens | 1 | ALA4665747 | cell-based format | Scientific Literature | |
5. | ALA4669629 | Functional | Induction of apoptosis in human HelaM cells assessed as increase in Bad level at 10 uM incubated for 24 hrs | Homo sapiens | 1 | ALA4665747 | cell-based format | Scientific Literature | |
6. | ALA4669630 | Functional | Induction of apoptosis in human HelaM cells assessed as increase in Akt level at 10 uM incubated for 24 hrs | Homo sapiens | 1 | ALA4665747 | cell-based format | Scientific Literature | |
7. | ALA4669631 | Functional | Induction of apoptosis in human HelaM cells assessed as increase in JNK level at 10 uM incubated for 24 hrs | Homo sapiens | 1 | ALA4665747 | cell-based format | Scientific Literature | |
8. | ALA4669632 | Functional | Induction of mitochondrial membrane potential loss in human HelaM cells assessed as cell population with intact mitochondrial membrane potential at 25 uM by JC-10 staining-based flow cytometric analysis (Rvb = 77.48 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
9. | ALA4669633 | Functional | Induction of mitochondrial membrane potential loss in human HelaM cells assessed as cell population with mitochondrial membrane potential collapse at 25 uM by JC-10 staining-based flow cytometric analysis (Rvb = 22.17 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
10. | ALA4669634 | Functional | Induction of mitochondrial membrane potential loss in human HelaM cells assessed as cell population with intact mitochondrial membrane potential at 10 uM by JC-10 staining-based flow cytometric analysis (Rvb = 77.48 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
11. | ALA4669635 | Functional | Induction of mitochondrial membrane potential loss in human HelaM cells assessed as cell population with mitochondrial membrane potential collapse at 10 uM by JC-10 staining-based flow cytometric analysis (Rvb = 22.17 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
12. | ALA4669636 | Functional | Induction of apoptosis in human HelaM cells assessed as viable cells at 25 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 93.33 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
13. | ALA4669637 | Functional | Induction of apoptosis in human HelaM cells assessed as necrotic cells at 25 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 4.55 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
14. | ALA4669638 | Functional | Induction of apoptosis in human HelaM cells assessed as late apoptotic cells at 25 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.62 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
15. | ALA4669639 | Functional | Induction of apoptosis in human HelaM cells assessed as early apoptotic cells at 25 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.5 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
16. | ALA4669640 | Functional | Induction of apoptosis in human HelaM cells assessed as viable cells at 10 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 93.33 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
17. | ALA4669641 | Functional | Induction of apoptosis in human HelaM cells assessed as necrotic cells at 10 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 4.55 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
18. | ALA4669642 | Functional | Induction of apoptosis in human HelaM cells assessed as late apoptotic cells at 10 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.62 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
19. | ALA4669643 | Functional | Induction of apoptosis in human HelaM cells assessed as early apoptotic cells at 10 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.5 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
20. | ALA4669644 | Functional | Potency index, ratio of doxorubicin IC50 to compound IC50 for cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by DAPI staining-based fluorescence assay | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature |