# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4729817 | B | Binding affinity to recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) assessed as adduct formation at 100 uM measured after 30 mins in presence of DTT by Q-TOF MS analysis | Homo sapiens | 3 | assay format | Scientific Literature | ||
2. | ALA4729828 | B | Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) at 1.1 to 90 uM using bovine insulin as substrate preincubated for 1 hr followed by substrate addition in presence of glutathione | Homo sapiens | 1 | assay format | Scientific Literature | ||
3. | ALA4729829 | B | Binding affinity to recombinant human wild-type N-terminal His-tagged PDIA1 C53S mutant expressed in Escherichia coli strain BL21(DE3) assessed as adduct formation at 100 uM measured after 30 mins in presence of DTT by Q-TOF MS analysis | Homo sapiens | 2 | assay format | Scientific Literature | ||
4. | ALA4729832 | F | Inhibition of colony formation in BSO-treated human U-87 MG cells at 0.3 to 30 uM measured after 10 to 14 days by crystal violet staining based assay | Homo sapiens | 2 | cell-based format | Scientific Literature |