# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4687820 | Binding | Induction of DNA damage in human K562 cells assessed as induction of DNA break formation by measuring H2AX phosphorylation at 10 uM incubated for 2 hrs by Western blot analysis | Homo sapiens | 12 | ALA4680284 | cell-based format | Scientific Literature | |
2. | ALA4687821 | Binding | Induction of DNA damage in human K562 cells assessed as induction of DNA break formation by measuring H2AX phosphorylation at 10 uM incubated for 2 hrs by constant-field gel electroporation method | Homo sapiens | 12 | ALA4680284 | cell-based format | Scientific Literature | |
3. | ALA4687822 | Functional | Induction of histone eviction in human MEL-JUSO cells assessed as release of photoactivated green fluorescent protein-labeled histone H2A at 10 uM incubated for 2 hrs by time-lapse confocal microscopy | Homo sapiens | 12 | ALA4680284 | cell-based format | Scientific Literature | |
4. | ALA4687823 | Functional | Cytotoxicity in human K562 cells assessed as reduction in cell viability incubated for 2 hrs by Cell-titer-blue assay | Homo sapiens | 12 | ALA4680284 | cell-based format | Scientific Literature | |
5. | ALA4687824 | Functional | Cytotoxicity in human MEL-JUSO cells assessed as reduction in cell viability incubated for 2 hrs by Cell-titer-blue assay | Homo sapiens | 12 | ALA4680284 | cell-based format | Scientific Literature | |
6. | ALA4687825 | Functional | Cytotoxicity in human HCT-116 cells assessed as reduction in cell viability incubated for 2 hrs by Cell-titer-blue assay | Homo sapiens | 12 | ALA4680284 | cell-based format | Scientific Literature | |
7. | ALA4687826 | Functional | Cytotoxicity in human PC-3 cells assessed as reduction in cell viability incubated for 2 hrs by Cell-titer-blue assay | Homo sapiens | 12 | ALA4680284 | cell-based format | Scientific Literature | |
8. | ALA4687827 | Functional | Cytotoxicity in human DU-145 cells assessed as reduction in cell viability incubated for 2 hrs by Cell-titer-blue assay | Homo sapiens | 12 | ALA4680284 | cell-based format | Scientific Literature | |
9. | ALA4687828 | Functional | Cytotoxicity in human U87 cells assessed as reduction in cell viability incubated for 2 hrs by Cell-titer-blue assay | Homo sapiens | 12 | ALA4680284 | cell-based format | Scientific Literature | |
10. | ALA4687829 | ADME | Drug uptake in human K562 cells at 1 uM by flow cytometry relative to doxorubicin | Homo sapiens | 5 | ALA4680284 | cell-based format | Scientific Literature | |
11. | ALA4687831 | Binding | Induction of relocalization of GFP-tagged Topo2a (unknown origin) expressed in human MEL-JUSO cells at 10 uM incubated for 15 mins | Homo sapiens | 12 | ALA4680284 | cell-based format | Scientific Literature |