| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4672669 | B | Inhibition of purified human plasma thrombin using Boc-Asp(OBzl)-Pro-Arg-AMC substrate incubated for 30 mins by fluorescence based assay | Homo sapiens | 56 | single protein format | Scientific Literature | ||
| 2. | ALA4672670 | A | Permeability from apical to basolateral side in human Caco2 cells incubated for 2 hrs by LC-MS/MS analysis | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
| 3. | ALA4672671 | A | Clearance in Wistar rat hepatocytes at 1 uM incubated up to 90 mins by LC-MS/MS analysis | Rattus norvegicus | 45 | cell-based format | Scientific Literature | ||
| 4. | ALA4672672 | A | Activation of human PXR expressed in human HepG2 cells | Homo sapiens | 45 | cell-based format | Scientific Literature | ||
| 5. | ALA4672676 | A | MRT in Wistar Hannover rat at 0.3 to 0.5 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
| 6. | ALA4672677 | A | AUC/dose in Wistar Hannover rat at 0.3 to 0.5 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
| 7. | ALA4672678 | A | Blood clearance in Wistar Hannover rat at 0.3 to 0.5 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 11 | organism-based format | Scientific Literature | ||
| 8. | ALA4672679 | A | Ratio of drug level in blood to plasma in Wistar Hannover rat at 0.3 to 0.5 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
| 9. | ALA4672680 | A | Volume of distribution at steady state in Wistar Hannover rat at 0.3 to 0.5 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
| 10. | ALA4672681 | A | Half life in Wistar Hannover rat at 0.3 to 0.5 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
| 11. | ALA4672682 | A | Oral bioavailability in Wistar Hannover rat at 1 mg/kg by LC-MS/MS analysis | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
| 12. | ALA4672683 | A | Activation of human PXR human hepatocytes assessed as induction of CYP3A4 mRNA expression incubated for 48 hrs by qPCR analysis | Homo sapiens | 10 | tissue-based format | Scientific Literature |
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