# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4710714 | B | Antagonist activity at NOD1 in HEK-Blue hNOD1 cells assessed as inhibition of C12-iE-DAP-induced NFkappaB activation-mediated SEAP release at 5 uM preincubated for 3 hrs followed by C12-iE-DAP addition and measured after 20 hrs by spectrophotometric method relative to control | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
2. | ALA4710715 | B | Antagonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as inhibition of MDP-induced NFkappaB activation-mediated SEAP release at 5 uM preincubated for 3 hrs followed by MDP addition and measured after 20 hrs by spectrophotometric method relative to control | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
3. | ALA4710716 | B | Antagonist activity at NOD1 in HEK-Blue hNOD1 cells assessed as inhibition of C12-iE-DAP-induced NFkappaB activation-mediated SEAP release preincubated for 3 hrs followed by C12-iE-DAP addition and measured after 20 hrs by spectrophotometric method | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
4. | ALA4710717 | B | Antagonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as inhibition of MDP-induced NFkappaB activation-mediated SEAP release preincubated for 3 hrs followed by MDP addition and measured after 20 hrs by spectrophotometric method | Homo sapiens | 46 | cell-based format | Scientific Literature | ||
5. | ALA4710718 | A | Half life in mouse liver microsomes at 1.25 uM preincubated for 5 mins followed by NADPH generating system addition and measured for 120 mins by LC-MS/MS analysis | Mus musculus | 7 | microsome format | Scientific Literature |