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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4665920 Functional Positive allosteric modulator activity at human mGlu4 receptor/Gqi5 in presence of EC20 glutamate by calcium mobilization assay Homo sapiens 34 ALA4665621 assay format Scientific Literature 2. ALA4665921 Functional Positive allosteric modulator activity at human mGlu4 receptor/Gqi5 assessed as maximum activity at 30 uM by calcium mobilization assay relative to glutamic acid Homo sapiens 29 ALA4665621 assay format Scientific Literature 3. ALA4665933 Functional Reversal of haloperidol-induced catalepsy in rat assessed as reduction in catalepsy at 3 mg/kg, po dosed along with 1.5 mg/kg haloperidol relative to untreated control Rattus norvegicus 4 ALA4665621 organism-based format Scientific Literature 4. ALA4665934 ADME Brain to plasma partition coefficient, Kp of the compound in Sprague-Dawley rat at 0.20 to 0.25 mg/kg, iv cassette dose measured at 0.25 hrs Rattus norvegicus 6 ALA4665621 organism-based format Scientific Literature 5. ALA4665935 Functional Positive allosteric modulator activity at rat mGlu4 receptor/Gqi5 in presence of EC20 glutamate by calcium mobilization assay Rattus norvegicus 1 ALA4665621 assay format Scientific Literature 6. ALA4665936 Functional Positive allosteric modulator activity at rat mGlu4 receptor/Gqi5 assessed as maximum activity by calcium mobilization assay relative to glutamic acid Rattus norvegicus 1 ALA4665621 assay format Scientific Literature 7. ALA4665937 ADME Inhibition of CYP2C19 (unknown origin) Homo sapiens 1 ALA4665621 single protein format Scientific Literature 8. ALA4665938 Functional Reversal of haloperidol-induced catalepsy in po dosed rat assessed as minimum effective dose Rattus norvegicus 1 ALA4665621 organism-based format Scientific Literature 9. ALA5258137 ADME Oral bioavailability in Cynomolgus monkey at 3 mg/kg administered as spray-dried dispersion formulation and measured upto 24 hrs by LC-MS/MS analysis Macaca fascicularis 1 ALA5257040 organism-based format Scientific Literature 10. ALA5258138 ADME AUC in Sprague-Dawley rat at 30 mg/kg, po administered as spray-dried dispersion formulation and measured after 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5257040 organism-based format Scientific Literature 11. ALA5258139 ADME AUC in Sprague-Dawley rat at 10 mg/kg, po administered as spray-dried dispersion formulation and measured after 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5257040 organism-based format Scientific Literature 12. ALA5258140 ADME AUC in Sprague-Dawley rat at 3 mg/kg, po administered as spray-dried dispersion formulation and measured after 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5257040 organism-based format Scientific Literature 13. ALA5258141 ADME Cmax in Sprague-Dawley rat at 30 mg/kg, po administered as spray-dried dispersion formulation and measured after 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5257040 organism-based format Scientific Literature 14. ALA5258142 ADME Cmax in Sprague-Dawley rat at 10 mg/kg, po administered as spray-dried dispersion formulation and measured after 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5257040 organism-based format Scientific Literature 15. ALA5258143 ADME Cmax in Sprague-Dawley rat at 3 mg/kg, po administered as spray-dried dispersion formulation and measured after 24 hrs by LC-MS/MS analysis Rattus norvegicus 1 ALA5257040 organism-based format Scientific Literature 16. ALA5258144 ADME Solubility of compound intestinal fluid assessed as AUC administered as spray-dried dispersion formulation 1 ALA5257040 assay format Scientific Literature 17. ALA5258145 ADME Solubility of compound intestinal fluid assessed as AUC administered as HPMCP-HP55 polymer formulation 1 ALA5257040 assay format Scientific Literature 18. ALA5258146 ADME Solubility of compound intestinal fluid assessed as AUC administered as active pharmaceutical ingredient (API) formulation 1 ALA5257040 assay format Scientific Literature 19. ALA5258147 Functional Reversal of haloperidol-induced catalepsy Sprague-Dawley rat model at 0.3 to 30 mg/kg,po and measured upto 6 hrs Rattus norvegicus 1 ALA5257040 organism-based format Scientific Literature 20. ALA5258148 ADME Drug uptake in cerebrospinal fluid of haloperidol-induced catalepsy Sprague-Dawley rat model at 0.3 to 30 mg/kg,po Rattus norvegicus 1 ALA5257040 organism-based format Scientific Literature