Assay

#	Aladdin ID	Assay Type	Description	Organism	Compounds	BAO Format	Source
1.	ALA4737518	F	Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay	Homo sapiens	42	cell-based format	Scientific Literature
2.	ALA4737519	F	Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay relative to relaxin	Homo sapiens	42	cell-based format	Scientific Literature
3.	ALA4737521	P	Aqueous solubility of compound in phosphate buffer at pH 7.4 measured after 24 hrs by UPLC analysis		13	small-molecule physicochemical format	Scientific Literature
4.	ALA4737527	A	Half life in Sprague-Dawley rat at 1 mg/kg, iv measured upto 72 hrs by LC-HRMS analysis	Rattus norvegicus	13	organism-based format	Scientific Literature
5.	ALA4737528	F	Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay	Homo sapiens	11	cell-based format	Scientific Literature
6.	ALA4737530	B	Selectivity ratio of EC50 for agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells in presence of 2 % HSA to EC50 for agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells in absence of HSA	Homo sapiens	8	cell-based format	Scientific Literature
7.	ALA4737537	A	Stability in human blood assessed as parent compound at 5 uM remaining after 4 hrs	Homo sapiens	2	tissue-based format	Scientific Literature
8.	ALA4737538	A	Stability in rat blood assessed as parent compound at 5 uM remaining after 4 hrs	Rattus norvegicus	2	tissue-based format	Scientific Literature