# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4773127 | F | Cytotoxicity against human DU-145 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 36 | ALA4765407 | cell-based format | Scientific Literature | |
2. | ALA4773129 | F | Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 10 | ALA4765407 | cell-based format | Scientific Literature | |
3. | ALA4773130 | F | Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 19 | ALA4765407 | cell-based format | Scientific Literature | |
4. | ALA4773131 | F | Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 20 | ALA4765407 | cell-based format | Scientific Literature | |
5. | ALA4773132 | F | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 27 | ALA4765407 | cell-based format | Scientific Literature | |
6. | ALA4773133 | F | Cytotoxicity against human UMUC3 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 13 | ALA4765407 | cell-based format | Scientific Literature | |
7. | ALA4773134 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 13 | ALA4765407 | cell-based format | Scientific Literature | |
8. | ALA4773135 | F | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 19 | ALA4765407 | cell-based format | Scientific Literature | |
9. | ALA4773136 | F | Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 31 | ALA4765407 | cell-based format | Scientific Literature | |
10. | ALA4773137 | F | Cytotoxicity against human MIA PaCa-2 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 25 | ALA4765407 | cell-based format | Scientific Literature | |
11. | ALA4773139 | F | Cytotoxicity against human ASPC1 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 19 | ALA4765407 | cell-based format | Scientific Literature | |
12. | ALA4773149 | F | Antitumour activity against Walker 256 adenocarcinoma cells implanted in Wistar rat assessed as increase in animal survival rate by measuring T/C ratio at 0.65 mg/kg, ip qd for 3 days administered on day 3,4,5 after tumor cell transplantation | Rattus norvegicus | 1 | ALA4765407 | organism-based format | Scientific Literature | |
13. | ALA4773172 | F | Antitumour activity against human NCI-H460 cells xenografted in Crl:Nu-Foxnl nu mouse assessed as inhibition of tumour growth at total effective dose of 5 mg/kg, iv measured on day 15 | Homo sapiens | 1 | ALA4765407 | organism-based format | Scientific Literature | |
14. | ALA4773187 | F | Antitumour activity against human NCI-H460 cells xenografted in Crl:Nu-Foxnl nu mouse assessed as inhibition of tumour growth at total effective dose of 16 mg/kg, iv measured on day 14 | Homo sapiens | 1 | ALA4765407 | organism-based format | Scientific Literature | |
15. | ALA4773188 | F | Antitumour activity against human PANC-1 cells xenografted in Crl:Nu-Foxnl nu mouse assessed as inhibition of tumour growth at total effective dose of 10 mg/kg, iv measured on day 45 | Homo sapiens | 1 | ALA4765407 | organism-based format | Scientific Literature | |
16. | ALA4773244 | B | Stabilization of 5'-FAM/3'-TAMRA labeled c-Myc promoter G4 quadruplex DNA FPu18 (unknown origin) assessed as change in melting temperature at 10 microM measured after 15 mins by FRET assay | Not specified | 22 | ALA4765407 | nucleic acid format | Scientific Literature | |
17. | ALA4773245 | B | Stabilization of 5'-FAM/3'-TAMRA labeled telomeric G4 quadruplex DNA F21T (unknown origin) assessed as change in melting temperature at 10 microM measured after 15 mins by FRET assay | Not specified | 22 | ALA4765407 | nucleic acid format | Scientific Literature | |
18. | ALA4773246 | B | Stabilization of 5'-FAM/3'-TAMRA labeled K-Ras G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 10 microM measured after 15 mins by FRET assay | Not specified | 22 | ALA4765407 | nucleic acid format | Scientific Literature |