| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4719346 | F | Antiviral activity against HIV-1 BAL infected in human astrocytes assessed as reduction in p24 production at 10 to 1000 nM treated for 1 hr prior to viral infection and measured after 5 days by ELISA | Human immunodeficiency virus 1 | 3 | organism-based format | Scientific Literature | ||
| 2. | ALA4719349 | F | Antagonist activity at human MOR transfected in CHO cells co-transfected with Gqi5 assessed as inhibition of DAMGO-induced calcium mobilization incubated for 15 mins prior to DAMGO addition and measured for 90 secs by Fluo-4AM dye based fluorescence analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA4719350 | B | Displacement of [3H]NLX from mouse MOR expressed in CHO cell membrane incubated for 90 mins by liquid scintillation spectrophotometry | Mus musculus | 8 | cell membrane format | Scientific Literature | ||
| 4. | ALA4719351 | F | Antagonist activity at CCR5 receptor in human MOLT4 cells transfected with Gqi5 assessed as inhibition of RANTES-induced calcium mobilization incubated for 15 mins prior to RANTES addition and measured for 120 secs by Fluo-4AM dye based fluorescence analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 5. | ALA4719352 | B | Displacement of [125I]MIP-1alpha from CCR5 receptor in rhesus monkey membrane incubated for 120 mins by liquid scintillation counting analysis | Macaca mulatta | 9 | cell membrane format | Scientific Literature | ||
| 6. | ALA4719355 | F | Agonist activity at CCR5 receptor in human MOLT4 cells transfected with Gqi5 assessed as calcium mobilization incubated for 15 mins by Fluo-4AM dye based fluorescence analysis | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA4719356 | F | Antiviral activity against HIV-1 BAL infected in human PBMC assessed as reduction in p24 production at 10 to 1000 nM treated for 1 hr prior to viral infection and measured after 5 days by ELISA | Human immunodeficiency virus 1 | 2 | organism-based format | Scientific Literature | ||
| 8. | ALA4719358 | F | Antiviral activity against HIV-1 BAL infected in human macrophages assessed as reduction in p24 production at 1 uM treated for 1 hr prior to viral infection and measured after 5 days by ELISA | Human immunodeficiency virus 1 | 3 | organism-based format | Scientific Literature |
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