# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4732638 | F | Cytotoxicity against human TF-1 cells expressing JAK2 assessed as reduction in cell viability incubated for 72 hrs by presto blue reagent assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
2. | ALA4732639 | F | Cytotoxicity against human HEL 92.1.7 cells expressing JAK2 assessed as reduction in cell viability incubated for 72 hrs by presto blue reagent assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA4732640 | A | Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 72 hrs by presto blue reagent assay | Chlorocebus sabaeus | 6 | cell-based format | Scientific Literature | ||
4. | ALA4732643 | B | Inhibition of recombinant human JAK2 JH1 domain expressed in baculovirus infected insect cells using poly-Glu-Tyr (51 to 68 residues) as substrate incubated for 1 hr in presence of ATP by ADP-Glo assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
5. | ALA4732644 | B | Inhibition of human EGFR TK domain expressed in Escherichia coli BL21 (DE3) pLysS using poly-Glu-Tyr (51 to 68 residues) as substrate incubated for 1 hr by ADP-Glo assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
6. | ALA4732646 | F | Potency index, ratio of ruxolitinib IC50 to test compound IC50 for human HEL 92.1.7 cells expressing JAK2 assessed as reduction in cell viability incubated for 72 hrs by presto blue reagent assay | Homo sapiens | 2 | tissue-based format | Scientific Literature |