# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4706997 | Physicochemical | Distribution coefficient, logD of compound at pH 7.4 | 19 | ALA4706476 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA4706998 | Binding | Displacement of FITC-geldanamycin from N-terminal HSP90alpha (unknown origin) after 30 mins by fluorescence polarization competitive binding assay | Homo sapiens | 49 | ALA4706476 | single protein format | Scientific Literature | |
3. | ALA4706999 | Functional | Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 49 | ALA4706476 | cell-based format | Scientific Literature | |
4. | ALA4707000 | Functional | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 49 | ALA4706476 | cell-based format | Scientific Literature | |
5. | ALA4707001 | ADME | Permeability of the compound at pH 7.4 by PAMPA | 22 | ALA4706476 | assay format | Scientific Literature | ||
6. | ALA4707002 | Physicochemical | Intrinsic aqueous solubility of the compound | 19 | ALA4706476 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4707003 | Binding | Displacement of FITC-geldanamycin from N-terminal GRP94 (unknown origin) after 30 mins by fluorescence polarization competitive binding assay | Homo sapiens | 23 | ALA4706476 | single protein format | Scientific Literature | |
8. | ALA4707004 | Binding | Selectivity ratio of IC50 for inhibition of FITC-geldanamycin binding to N-terminal GRP94 (unknown origin) to IC50 for inhibition of FITC-geldanamycin binding to N-terminal HSP90alpha (unknown origin) | 23 | ALA4706476 | assay format | Scientific Literature | ||
9. | ALA4707005 | Functional | Antiproliferative activity against human MDA-MB-231 assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature | |
10. | ALA4707006 | Functional | Antiproliferative activity against human MDA-MB-468 assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature | |
11. | ALA4707007 | Functional | Antiproliferative activity against human SK-BR-3 assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature | |
12. | ALA4707008 | Functional | Antiproliferative activity against human T47D assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature | |
13. | ALA4707009 | Functional | Antiproliferative activity against human BT-474 assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature | |
14. | ALA4707010 | Functional | Antiproliferative activity against human U2OS assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature | |
15. | ALA4707011 | Functional | Antiproliferative activity against human MKN-28 assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature | |
16. | ALA4707012 | Functional | Antiproliferative activity against human A549 assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature | |
17. | ALA4707013 | Functional | Antiproliferative activity against human HepG2 assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature | |
18. | ALA4707014 | Functional | Antiproliferative activity against human K562 assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature | |
19. | ALA4707015 | Functional | Antiproliferative activity against human MV4-11 assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature | |
20. | ALA4707016 | ADME | Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 4 | ALA4706476 | cell-based format | Scientific Literature |