# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4769246 | Binding | Inhibition of TNNI3K (unknown origin) assessed as residual activity at 1 uM using biotinylated CTnI as substrate by HTRF analysis relative to control | Homo sapiens | 35 | ALA4765301 | single protein format | Scientific Literature | |
2. | ALA4769247 | Binding | Inhibition of recombinant human EGFR (696 to end residues) assessed as residual activity at 1 uM using poly(Glu, Tyr) 4:1 as substrate incubated for 40 mins by [gamma-33P]-ATP scintillation counting based radiometry assay relative to control | Homo sapiens | 35 | ALA4765301 | single protein format | Scientific Literature | |
3. | ALA4769248 | Binding | Inhibition of recombinant human HER2 (676 to end residues) assessed as residual activity at 1 uM using poly(Glu, Tyr) 4:1 as substrate incubated for 40 mins by [gamma-33P]-ATP scintillation counting based radiometry assay relative to control | Homo sapiens | 35 | ALA4765301 | single protein format | Scientific Literature | |
4. | ALA4769249 | Binding | Inhibition of recombinant human FLT1 (783 to end residues) assessed as residual activity at 1 uM using KKKSPGEYVNIEFG as substrate incubated for 40 mins by [gamma-33P]-ATP scintillation counting based radiometry assay relative to control | Homo sapiens | 35 | ALA4765301 | single protein format | Scientific Literature | |
5. | ALA4769250 | Binding | Inhibition of recombinant human KDR (790 to end residues) assessed as residual activity at 1 uM using myelin basic protein as substrate incubated for 40 mins by [gamma-33P]-ATP scintillation counting based radiometry assay relative to control | Homo sapiens | 35 | ALA4765301 | single protein format | Scientific Literature | |
6. | ALA4769251 | Binding | Inhibition of TNNI3K (unknown origin) using biotinylated CTnI as substrate by HTRF analysis | Homo sapiens | 11 | ALA4765301 | single protein format | Scientific Literature | |
7. | ALA4769252 | Functional | Cytoprotective activity against OGD-induced cell death in rat H9c2 cells assessed as cell viability at 1 uM incubated for 24 hrs by MTT assay (Rvb = 42.08 to 49.11 %) | Rattus norvegicus | 11 | ALA4765301 | cell-based format | Scientific Literature | |
8. | ALA4769253 | Functional | Cytoprotective activity against OGD-induced cell death in rat H9c2 cells assessed as cell viability at 10 uM incubated for 24 hrs by MTT assay (Rvb = 42.08 to 49.11 %) | Rattus norvegicus | 11 | ALA4765301 | cell-based format | Scientific Literature | |
9. | ALA4769254 | Functional | Inhibition of OGD-induced apoptosis in rat H9c2 cells incubated for 24 hrs by annexinV-FITC and PI staining based flow cytometry analysis | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature | |
10. | ALA4769255 | Functional | Inhibition of OGD-induced apoptosis in rat H9c2 cells assessed as viable cells at 0.5 uM incubated for 24 hrs by annexinV-FITC and PI staining based flow cytometry analysis (Rvb = 85 %) | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature | |
11. | ALA4769256 | Functional | Inhibition of OGD-induced apoptosis in rat H9c2 cells assessed as early apoptotic cells at 0.5 uM incubated for 24 hrs by annexinV-FITC and PI staining based flow cytometry analysis (Rvb = 3.53 %) | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature | |
12. | ALA4769257 | Functional | Inhibition of OGD-induced apoptosis in rat H9c2 cells assessed as late apoptotic cells at 0.5 uM incubated for 24 hrs by annexinV-FITC and PI staining based flow cytometry analysis (Rvb = 9 %) | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature | |
13. | ALA4769258 | Functional | Inhibition of OGD-induced apoptosis in rat H9c2 cells assessed as necrotic cells at 0.5 uM incubated for 24 hrs by annexinV-FITC and PI staining based flow cytometry analysis (Rvb = 2.45 %) | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature | |
14. | ALA4769259 | Functional | Inhibition of OGD-induced apoptosis in rat H9c2 cells assessed as viable cells at 1 uM incubated for 24 hrs by annexinV-FITC and PI staining based flow cytometry analysis (Rvb = 85 %) | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature | |
15. | ALA4769260 | Functional | Inhibition of OGD-induced apoptosis in rat H9c2 cells assessed as early apoptotic cells at 1 uM incubated for 24 hrs by annexinV-FITC and PI staining based flow cytometry analysis (Rvb = 3.53 %) | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature | |
16. | ALA4769261 | Functional | Inhibition of OGD-induced apoptosis in rat H9c2 cells assessed as late apoptotic cells at 1 uM incubated for 24 hrs by annexinV-FITC and PI staining based flow cytometry analysis (Rvb = 9 %) | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature | |
17. | ALA4769262 | Functional | Inhibition of OGD-induced apoptosis in rat H9c2 cells assessed as necrotic cells at 1 uM incubated for 24 hrs by annexinV-FITC and PI staining based flow cytometry analysis (Rvb = 2.45 %) | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature | |
18. | ALA4769263 | Functional | Cytoprotective activity against OGD-induced cell death in rat H9c2 cells assessed as cell viability incubated for 24 hrs by LDH release assay | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature | |
19. | ALA4769264 | Functional | Inhibition of OGD-induced apoptosis in rat H9c2 cells assessed as reduction in cytochromeC level by Western blot analysis | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature | |
20. | ALA4769265 | Binding | Inhibition of TNNI3K in rat H9c2 cells assessed as reduction in p38 phosphorylation at 0.5 to 1 uM by Western blot analysis | Rattus norvegicus | 1 | ALA4765301 | cell-based format | Scientific Literature |