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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4770795 B Upregulation of Runx2 transcriptional activity in mouse MC3T3-E1 cells transfected with p6OSE2-luc at 100 uM incubated for 48 hrs by firefly luciferase reporter gene assay relative to control Mus musculus 1 cell-based format Scientific Literature 2. ALA4770797 T Toxicity in BALB/c mouse assessed as muscle spasm at 50 to 100 mg/kg, ig administered for 14 days Mus musculus 2 organism-based format Scientific Literature 3. ALA4770798 T Toxicity in BALB/c mouse assessed as convulsion at 50 to 100 mg/kg, ig administered for 14 days Mus musculus 2 organism-based format Scientific Literature 4. ALA4770799 T Toxicity in BALB/c mouse assessed as fremitus at 50 to 100 mg/kg, ig administered for 14 days Mus musculus 2 organism-based format Scientific Literature 5. ALA4770800 T Toxicity in BALB/c mouse assessed as effect on body weight at 50 to 100 mg/kg, ig administered for 14 days Mus musculus 2 organism-based format Scientific Literature 6. ALA4770801 T Toxicity in BALB/c mouse assessed as effect on hair at 50 to 100 mg/kg, ig administered for 14 days Mus musculus 2 organism-based format Scientific Literature 7. ALA4770802 A Oral bioavailability in Sprague-Dawley rat at 10 mg/kg by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 8. ALA4770803 A AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, po by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 9. ALA4770804 A Cmax in Sprague-Dawley rat at 10 mg/kg, po by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 10. ALA4770805 A AUC (0 to t) in Sprague-Dawley rat at 10 mg/kg, po by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 11. ALA4770806 A Half life in Sprague-Dawley rat at 10 mg/kg, po by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 12. ALA4770807 A Tmax in Sprague-Dawley rat at 10 mg/kg, po by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 13. ALA4770808 A MRT in Sprague-Dawley rat at 2 mg/kg, iv by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 14. ALA4770809 A AUC (0 to t) in Sprague-Dawley rat at 2 mg/kg, iv by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 15. ALA4770810 A AUC (0 to infinity) in Sprague-Dawley rat at 2 mg/kg, iv by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 16. ALA4770811 A Initial concentration in Sprague-Dawley rat at 2 mg/kg, iv by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 17. ALA4770812 A Half life in Sprague-Dawley rat at 2 mg/kg, iv by LC-MS/MS analysis Rattus norvegicus 1 organism-based format Scientific Literature 18. ALA4770820 T Toxicity in Kunming mouse assessed as organism death administered orally for 3 days and observed for 17 days starting from drug administration Mus musculus 5 assay format Scientific Literature 19. ALA4770821 F Antiosteoporotic activity in Sprague-Dawley rat model of OVX-induced bone loss assessed as increase in number of trabeculae at 30 mg/kg, ig administered for 3 months with 1 day break after 6 consecutive days administration Rattus norvegicus 4 organism-based format Scientific Literature 20. ALA4770822 F Antiosteoporotic activity in Sprague-Dawley rat model of OVX-induced bone loss assessed as increase in thickness of trabeculae at 30 mg/kg, ig administered for 3 months with 1 day break after 6 consecutive days administration Rattus norvegicus 4 organism-based format Scientific Literature