# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4710418 | B | Inhibition of Mycobacterium tuberculosis DprE1 expressed in Escherichia coli BL21 (DE3) cells assessed as formation of resorufin using FPR as substrate by Amplex Red hydrogen/peroxidase coupled assay | Mycobacterium tuberculosis | 16 | cell-based format | Scientific Literature | ||
2. | ALA4710419 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv ATCC 25618 assessed as inhibition of visible bacterial growth by MABA assay | Mycobacterium tuberculosis | 18 | organism-based format | Scientific Literature | ||
3. | ALA4710429 | B | Inhibition of Mycobacterium tuberculosis H37Rv DprE1 assessed as increase in trehalose dimycolates at 10 x MIC preincubated for 24 hrs using [14C]acetate by TLC based metabolic labelling assay relative to control | Mycobacterium tuberculosis H37Rv | 5 | single protein format | Scientific Literature | ||
4. | ALA4710430 | B | Inhibition of Mycobacterium tuberculosis H37Rv DprE1 assessed as increase in trehalose monomycolates at 10 x MIC preincubated for 24 hrs using [14C]acetate by TLC based metabolic labelling assay relative to control | Mycobacterium tuberculosis H37Rv | 5 | single protein format | Scientific Literature |