#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4772460	F	Agonist activity at human TGR5 expressed in HEK293 cells assessed as CRE-driven luciferase reporter gene activity incubated for 5.5 hrs and measured by Steady Glow reagent based luminescence assay	Homo sapiens	15	ALA4765387	cell-based format	Scientific Literature
2.	ALA4772461	F	Agonist activity at mouse TGR5 expressed in HEK293 cells assessed as CRE-driven luciferase reporter incubated for 5.5 hrs and measured by Steady Glow reagent based luminescence assay	Mus musculus	15	ALA4765387	cell-based format	Scientific Literature
3.	ALA4772463	F	Induction of GLP-1 secretion in human NCI-H716 cells after 2 hrs by ELISA	Homo sapiens	1	ALA4765387	cell-based format	Scientific Literature
4.	ALA4772464	F	In vivo agonist activity at TGR5 in ICR mouse assessed as induction of plasma GLP-1 level at 50 mg/kg, po after 4 hrs by ELISA relative to control	Mus musculus	1	ALA4765387	organism-based format	Scientific Literature
5.	ALA4772465	F	Antihyperglycemic activity in fasted ICR mouse assessed as reduction in blood glucose levels at 50 mg/kg, po measured upto 120 mins by OGTT method relative to control	Mus musculus	2	ALA4765387	organism-based format	Scientific Literature
6.	ALA4772466	A	Cmax in overnight-fasted ICR mouse systemic circulation at 50 mg/kg, po measured after 1 hr by LC-MS/MS analysis	Mus musculus	1	ALA4765387	organism-based format	Scientific Literature
7.	ALA4772467	F	Antihyperglycemic activity in overnight fasted ICR mouse assessed as reduction in blood glucose AUC (0 to 120 mins) at 50 mg/kg, po measured upto 120 mins by OGTT method relative to control	Mus musculus	2	ALA4765387	organism-based format	Scientific Literature
8.	ALA4772468	T	Toxicity against ICR mouse assessed as increase in gallbladder volume at 50 mg/kg, po administered for 3 days relative to control	Mus musculus	2	ALA4765387	organism-based format	Scientific Literature
9.	ALA4772469	T	Toxicity against ICR mouse assessed as increase in bile weight at 50 mg/kg, po administered for 3 days by analytical balance relative to control	Mus musculus	2	ALA4765387	organism-based format	Scientific Literature
10.	ALA4772470	F	In vivo agonist activity at TGR5 in ICR mouse assessed as induction of level GLP-1 level at 50 mg/kg, po in presence of linagliptin DPP4 inhibitor by ELISA relative to control	Mus musculus	1	ALA4765387	organism-based format	Scientific Literature
11.	ALA4772471	A	Cmax in overnight-fasted ICR mouse systemic circulation assessed as 5-[3-(4-Cyclopropyl-3,4-dihydro-2H-quinoxaline-1-carbonyl)-pyridin-4-yloxy]-benzofuran-3-carboxylic acid at 50 mg/kg, po measured after 1 hr by LC-MS/MS analysis	Mus musculus	1	ALA4765387	organism-based format	Scientific Literature
12.	ALA4772472	A	Cmax in overnight-fasted ICR mouse gallbladder tissue assessed as 5-[3-(4-Cyclopropyl-3,4-dihydro-2H-quinoxaline-1-carbonyl)-pyridin-4-yloxy]-benzofuran-3-carboxylic acid at 50 mg/kg, po measured after 1 hr by LC-MS/MS analysis	Mus musculus	1	ALA4765387	organism-based format	Scientific Literature
13.	ALA4772473	A	Cmax in overnight-fasted ICR mouse bile assessed as 5-[3-(4-Cyclopropyl-3,4-dihydro-2H-quinoxaline-1-carbonyl)-pyridin-4-yloxy]-benzofuran-3-carboxylic acid at 50 mg/kg, po measured after 1 hr by LC-MS/MS analysis	Mus musculus	1	ALA4765387	organism-based format	Scientific Literature
14.	ALA4772474	A	Peak drug concentration in overnight-fasted ICR mouse ileum at 50 mg/kg, po measured after 2 hr by LC-MS/MS analysis	Mus musculus	1	ALA4765387	organism-based format	Scientific Literature
15.	ALA4772475	A	Peak drug concentration in overnight-fasted ICR mouse colon at 50 mg/kg, po measured after 4 hr by LC-MS/MS analysis	Mus musculus	1	ALA4765387	organism-based format	Scientific Literature