| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4679635 | Binding | Disruption of cell membrane in methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as complete rupture of bacterial cell surface at 9 ug/ml incubated for 3 hrs by scanning electron microscopy | Staphylococcus aureus | 1 | ALA4673388 | subcellular format | Scientific Literature | |
| 2. | ALA4679636 | ADME | Cytotoxicity against human HEK293 cells up to 90 ug/ml measured after 48 hrs compound conjugated on alpha-helical coiled-coil FF03 peptide by CCK8 assay | Homo sapiens | 1 | ALA4673388 | cell-based format | Scientific Literature | |
| 3. | ALA4679637 | ADME | Cytotoxicity against human HEK293 cells up to 90 ug/ml measured after 48 hrs by CCK8 assay | Homo sapiens | 1 | ALA4673388 | cell-based format | Scientific Literature | |
| 4. | ALA4679638 | ADME | Cytotoxicity against human MCF7 cells up to 90 ug/ml measured after 48 hrs compound conjugated on alpha-helical coiled-coil FF03 peptide by CCK8 assay | Homo sapiens | 1 | ALA4673388 | cell-based format | Scientific Literature | |
| 5. | ALA4679639 | ADME | Cytotoxicity against human MCF7 cells up to 90 ug/ml measured after 48 hrs by CCK8 assay | Homo sapiens | 1 | ALA4673388 | cell-based format | Scientific Literature | |
| 6. | ALA4679640 | ADME | Hemolytic activity in human red blood cells at 100 ug/ml incubated for 45 mins compound conjugated on alpha-helical colied-coil FF03 peptide | Homo sapiens | 1 | ALA4673388 | cell-based format | Scientific Literature | |
| 7. | ALA4679641 | ADME | Hemolytic activity in human red blood cells at 100 ug/ml incubated for 45 mins | Homo sapiens | 1 | ALA4673388 | cell-based format | Scientific Literature | |
| 8. | ALA4679642 | Functional | Bactericidal activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as reduction in bacterial growth at MIC compound conjugated on alpha-helical coiled-coil FF03 peptide measured within 5 hrs by time kill assay | Staphylococcus aureus | 1 | ALA4673388 | organism-based format | Scientific Literature | |
| 9. | ALA4679643 | Functional | Bactericidal activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as reduction in bacterial growth at MIC measured for 25 hrs by time kill assay | Staphylococcus aureus | 1 | ALA4673388 | organism-based format | Scientific Literature | |
| 10. | ALA4679644 | Functional | Antibacterial activity against Pseudomonas aeruginosa ATCC 15442 assessed as inhibition of bacterial growth incubated for 16 to 20 hrs compound conjugated on alpha-helical coiled-coil FF03 peptide by microdilution method | Pseudomonas aeruginosa | 1 | ALA4673388 | organism-based format | Scientific Literature | |
| 11. | ALA4679645 | Functional | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as inhibition of bacterial growth incubated for 16 to 20 hrs compound conjugated on alpha-helical coiled-coil FF03 peptide by microdilution method | Staphylococcus aureus | 1 | ALA4673388 | organism-based format | Scientific Literature | |
| 12. | ALA4679646 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as inhibition of bacterial growth incubated for 16 to 20 hrs compound conjugated on alpha-helical coiled-coil FF03 peptide by microdilution method | Staphylococcus aureus | 1 | ALA4673388 | organism-based format | Scientific Literature | |
| 13. | ALA4679647 | Functional | Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth incubated for 16 to 20 hrs compound conjugated on alpha-helical coiled-coil FF03 peptide by microdilution method | Escherichia coli | 1 | ALA4673388 | organism-based format | Scientific Literature | |
| 14. | ALA4679648 | Functional | Antibacterial activity against Pseudomonas aeruginosa ATCC 15442 assessed as inhibition of bacterial growth incubated for 16 to 20 hrs by microdilution method | Pseudomonas aeruginosa | 2 | ALA4673388 | organism-based format | Scientific Literature | |
| 15. | ALA4679649 | Functional | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 assessed as inhibition of bacterial growth incubated for 16 to 20 hrs by microdilution method | Staphylococcus aureus | 6 | ALA4673388 | organism-based format | Scientific Literature | |
| 16. | ALA4679650 | Functional | Antibacterial activity against Staphylococcus aureus ATCC 25923 assessed as inhibition of bacterial growth incubated for 16 to 20 hrs by microdilution method | Staphylococcus aureus | 3 | ALA4673388 | organism-based format | Scientific Literature | |
| 17. | ALA4679651 | Functional | Antibacterial activity against Escherichia coli ATCC 25922 assessed as inhibition of bacterial growth incubated for 16 to 20 hrs by microdilution method | Escherichia coli | 2 | ALA4673388 | organism-based format | Scientific Literature |
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