# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4678701 | Functional | Antiproliferative activity against human NCI-H292 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | ALA4673347 | cell-based format | Scientific Literature | |
2. | ALA4678702 | Binding | Inhibition of recombinant human full length His-tagged PI3Kalpha expressed in baculovirus expression system using PIP2 as substrate by ADP-Glo reagent based assay | Homo sapiens | 23 | ALA4673347 | assay format | Scientific Literature | |
3. | ALA4678703 | Functional | Antiproliferative activity against human HGC-27 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 23 | ALA4673347 | cell-based format | Scientific Literature | |
4. | ALA4678704 | Binding | Inhibition of PI3K signalling in human HGC-27 cells assessed as reduction in AKT S473 phosphorylation incubated for 3 hrs by Western blot analysis | Homo sapiens | 2 | ALA4673347 | cell-based format | Scientific Literature | |
5. | ALA4678705 | Binding | Inhibition of PI3K signalling in human HGC-27 cells assessed as reduction in S6RP S235/236 phosphorylation incubated for 3 hrs by Western blot analysis | Homo sapiens | 2 | ALA4673347 | cell-based format | Scientific Literature | |
6. | ALA4678706 | Binding | Inhibition of PI3K signalling in human HGC-27 cells assessed as reduction in 4E-BP1 phosphorylation incubated for 3 hrs by Western blot analysis | Homo sapiens | 2 | ALA4673347 | cell-based format | Scientific Literature | |
7. | ALA4678707 | Functional | Induction of cell cycle arrest in human HGC-27 cells assessed as G0/G1 phase incubated for 24 hrs by propidium iodide staining based flow cytometry analysis | Homo sapiens | 2 | ALA4673347 | cell-based format | Scientific Literature | |
8. | ALA4678708 | Functional | Induction of apoptosis in human HGC-27 cells assessed as viable cells at 500 nM incubated for 24 hrs by annexin V-FITC and propidium iodide based staining based flow cytometry analysis (Rvb = 83.7 %) | Homo sapiens | 3 | ALA4673347 | cell-based format | Scientific Literature | |
9. | ALA4678709 | Functional | Induction of apoptosis in human HGC-27 cells assessed as early apoptotic cells at 500 nM incubated for 24 hrs by annexin V-FITC and propidium iodide based staining based flow cytometry analysis (Rvb = 6.22 %) | Homo sapiens | 3 | ALA4673347 | cell-based format | Scientific Literature | |
10. | ALA4678710 | Functional | Induction of apoptosis in human HGC-27 cells assessed as late apoptotic cells at 500 nM incubated for 24 hrs by annexin V-FITC and propidium iodide based staining based flow cytometry analysis (Rvb = 8.15 %) | Homo sapiens | 3 | ALA4673347 | cell-based format | Scientific Literature | |
11. | ALA4678711 | Functional | Induction of apoptosis in human HGC-27 cells assessed as necrotic cells at 500 nM incubated for 24 hrs by annexin V-FITC and propidium iodide based staining based flow cytometry analysis (Rvb = 1.95 %) | Homo sapiens | 3 | ALA4673347 | cell-based format | Scientific Literature | |
12. | ALA4678712 | Binding | Inhibition of recombinant human PI3Kbeta using PIP2 as substrate by ADP-Glo reagent based assay | Homo sapiens | 2 | ALA4673347 | single protein format | Scientific Literature | |
13. | ALA4678713 | Binding | Inhibition of recombinant human full length His-tagged PI3Kdelta expressed in baculovirus expression system using PIP2 as substrate by ADP-Glo reagent based assay | Homo sapiens | 2 | ALA4673347 | assay format | Scientific Literature | |
14. | ALA4678714 | Binding | Inhibition of recombinant human GST-tagged PI3Kgamma (468 to 1203 residues) expressed in insect expression system using PIP2 as substrate by ADP-Glo reagent based assay | Homo sapiens | 2 | ALA4673347 | assay format | Scientific Literature | |
15. | ALA4678715 | Functional | Antiproliferative activity against human BGC-823 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | ALA4673347 | cell-based format | Scientific Literature | |
16. | ALA4678716 | Functional | Antiproliferative activity against human AGS cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | ALA4673347 | cell-based format | Scientific Literature | |
17. | ALA4678717 | Functional | Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | ALA4673347 | cell-based format | Scientific Literature | |
18. | ALA4678718 | Functional | Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | ALA4673347 | cell-based format | Scientific Literature | |
19. | ALA4678719 | Functional | Antiproliferative activity against human KATO III stomach cancer cell line cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | ALA4673347 | tissue-based format | Scientific Literature | |
20. | ALA4678720 | Functional | Antiproliferative activity against human MKN-45 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | ALA4673347 | cell-based format | Scientific Literature |