| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4678701 | F | Antiproliferative activity against human NCI-H292 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4678702 | B | Inhibition of recombinant human full length His-tagged PI3Kalpha expressed in baculovirus expression system using PIP2 as substrate by ADP-Glo reagent based assay | Homo sapiens | 23 | assay format | Scientific Literature | ||
| 3. | ALA4678703 | F | Antiproliferative activity against human HGC-27 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 4. | ALA4678704 | B | Inhibition of PI3K signalling in human HGC-27 cells assessed as reduction in AKT S473 phosphorylation incubated for 3 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4678705 | B | Inhibition of PI3K signalling in human HGC-27 cells assessed as reduction in S6RP S235/236 phosphorylation incubated for 3 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4678706 | B | Inhibition of PI3K signalling in human HGC-27 cells assessed as reduction in 4E-BP1 phosphorylation incubated for 3 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4678707 | F | Induction of cell cycle arrest in human HGC-27 cells assessed as G0/G1 phase incubated for 24 hrs by propidium iodide staining based flow cytometry analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4678708 | F | Induction of apoptosis in human HGC-27 cells assessed as viable cells at 500 nM incubated for 24 hrs by annexin V-FITC and propidium iodide based staining based flow cytometry analysis (Rvb = 83.7 %) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA4678709 | F | Induction of apoptosis in human HGC-27 cells assessed as early apoptotic cells at 500 nM incubated for 24 hrs by annexin V-FITC and propidium iodide based staining based flow cytometry analysis (Rvb = 6.22 %) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4678710 | F | Induction of apoptosis in human HGC-27 cells assessed as late apoptotic cells at 500 nM incubated for 24 hrs by annexin V-FITC and propidium iodide based staining based flow cytometry analysis (Rvb = 8.15 %) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4678711 | F | Induction of apoptosis in human HGC-27 cells assessed as necrotic cells at 500 nM incubated for 24 hrs by annexin V-FITC and propidium iodide based staining based flow cytometry analysis (Rvb = 1.95 %) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4678712 | B | Inhibition of recombinant human PI3Kbeta using PIP2 as substrate by ADP-Glo reagent based assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 13. | ALA4678713 | B | Inhibition of recombinant human full length His-tagged PI3Kdelta expressed in baculovirus expression system using PIP2 as substrate by ADP-Glo reagent based assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 14. | ALA4678714 | B | Inhibition of recombinant human GST-tagged PI3Kgamma (468 to 1203 residues) expressed in insect expression system using PIP2 as substrate by ADP-Glo reagent based assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 15. | ALA4678715 | F | Antiproliferative activity against human BGC-823 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4678716 | F | Antiproliferative activity against human AGS cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4678717 | F | Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4678718 | F | Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4678719 | F | Antiproliferative activity against human KATO III stomach cancer cell line cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 20. | ALA4678720 | F | Antiproliferative activity against human MKN-45 cells assessed as reduction in cell viability incubated for 72 hrs measured after 4 hrs of MTT addition by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature |
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