| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4766119 | F | Antiangiogenesis activity in EGFP-labelled zebrafish embryo assessed as reduction in formation of dorsal aorta at 1.25 to 5 uM incubated for overnight by fluorescence microscopic analysis | Danio rerio | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA4766120 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 55 | cell-based format | Scientific Literature | ||
| 3. | ALA4766121 | F | Antiproliferative activity against human MDA-MB-435 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 55 | cell-based format | Scientific Literature | ||
| 4. | ALA4766122 | A | Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 55 | cell-based format | Scientific Literature | ||
| 5. | ALA4766123 | F | Antitumor activity against human MDA-MB-231 cells xenografted in SCID mouse assessed as tumor growth inhibition at 40 mg/kg, po qd for 15 days and measured every 3 days | Homo sapiens | 7 | organism-based format | Scientific Literature | ||
| 6. | ALA4766124 | F | Antitumor activity against human MDA-MB-231 cells xenografted in SCID mouse assessed as tumor growth inhibition at 40 mg/kg, po qd for 21 days and measured every 3 days | Homo sapiens | 7 | organism-based format | Scientific Literature | ||
| 7. | ALA4766125 | T | Toxicity in SCID mouse xenografted with MDA-MB-231 cells assessed as change in body weight at 40 mg/kg, po qd for 15 days and measured every 3 days | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 8. | ALA4766127 | T | Toxicity in SCID mouse xenografted with MDA-MB-231 cells assessed as animal death at 40 mg/kg, po qd for 15 days | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 9. | ALA4766129 | B | Inhibition of human full length recombinant Src using Cdc2 peptide as substrate incubated for 40 mins in presence of [gamma33P-ATP] by radiometric scintillation counting analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4766130 | B | Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by automated Qpatch electrophysiological assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 11. | ALA4766133 | A | Half-life in Sprague-Dawley rat at 10 mg/kg, po administered via gavage by LC-MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 12. | ALA4766134 | A | AUC (0 to t) in Sprague-Dawley rat at 10 mg/kg, po administered via gavage by LC-MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA4766135 | A | AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, po administered via gavage by LC-MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA4766136 | A | Tmax in Sprague-Dawley rat at 10 mg/kg, po administered via gavage by LC-MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA4766137 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po administered via gavage by LC-MS analysis | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA4766138 | A | Metabolic stability in mouse liver microsomes assessed as parent compound remaining at 1 uM measured after 60 mins in presence of NADPH by HPLC-MS/MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 17. | ALA4766139 | A | Metabolic stability in rat liver microsomes assessed as parent compound remaining at 1 uM measured after 60 mins in presence of NADPH by HPLC-MS/MS analysis | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 18. | ALA4766140 | A | Metabolic stability in dog liver microsomes assessed as parent compound remaining at 1 uM measured after 60 mins in presence of NADPH by HPLC-MS/MS analysis | Canis lupus familiaris | 1 | microsome format | Scientific Literature | ||
| 19. | ALA4766141 | A | Metabolic stability in monkey liver microsomes assessed as parent compound remaining at 1 uM measured after 60 mins in presence of NADPH by HPLC-MS/MS analysis | Macaca mulatta | 1 | microsome format | Scientific Literature | ||
| 20. | ALA4766142 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining at 1 uM measured after 60 mins in presence of NADPH by HPLC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature |
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