| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4685761 | B | Protac activity at CRBN/BCL-XL in human MOLT-4 cells assessed as induction of BCL-XL degradation measured after 16 hrs by immunoblotting analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA4685762 | F | Antiproliferative activity against human MOLT-4 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 56 | cell-based format | Scientific Literature | ||
| 3. | ALA4685765 | B | Protac activity at CRBN/BCL-XL in human MOLT-4 cells assessed as induction of BCL-XL degradation by measuring remaining BCL-XL level at 50 nM measured after 16 hrs by immunoblotting analysis relative to control | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 4. | ALA4685766 | B | Protac activity at CRBN/BCL2 in human MOLT-4 cells assessed as induction of BCL2 degradation at 50 nM measured after 16 hrs by immunoblotting analysis | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
| 5. | ALA4685768 | F | Antiproliferative activity against human RS4-11 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 6. | ALA4685769 | F | Antiproliferative activity against human NCI-H146 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 7. | ALA4685770 | T | Toxicity in human platelet assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 8 | tissue-based format | Scientific Literature | ||
| 8. | ALA4685771 | U | Selectivity index, ratio of IC50 for human platelet to IC50 for human MOLT-4 cells | Homo sapiens | 8 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!