| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4775585 | B | Inhibition of rat alpha-2,3-N-ST3GALIII assessed as reduction in sialylated-product formation using Gal-beta1-4Glc and CMP-NeuSAc incubated for 1.5 hrs by reverse-phase HPLC analysis | Rattus norvegicus | 19 | single protein format | Scientific Literature | ||
| 2. | ALA4775586 | B | Inhibition of human alpha-2,6-ST6GAL1 assessed as reduction in sialylated-product formation using Gal-beta1-4GlcNac and CMP-NeuSAc incubated for 15 mins by reverse-phase HPLC analysis | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 3. | ALA4775588 | B | Inhibition of rat alpha-2,3-O-ST3GALI assessed as reduction in sialylated-product formation at 500 uM using p-nitrophenyl T-antigen and CMP-NeuSAc incubated for 15 mins by reverse-phase HPLC analysis relative to control | Rattus norvegicus | 17 | single protein format | Scientific Literature | ||
| 4. | ALA4775589 | B | Inhibition of rat alpha-2,3-O-ST3GALI assessed as reduction in sialylated-product formation at 1 mM using p-nitrophenyl T-antigen and CMP-NeuSAc incubated for 15 mins by reverse-phase HPLC analysis relative to control | Rattus norvegicus | 5 | single protein format | Scientific Literature | ||
| 5. | ALA4775591 | B | Selectivity ratio of inhibition of rat alpha-2,3-O-ST3GALI at 500 uM to IC50 for inhibition of rat alpha-2,3-N-ST3GALIII | Rattus norvegicus | 5 | assay format | Scientific Literature | ||
| 6. | ALA4775592 | B | Selectivity ratio of inhibition of rat alpha-2,3-O-ST3GALI at 1000 uM to IC50 for inhibition of rat alpha-2,3-N-ST3GALIII | Rattus norvegicus | 3 | assay format | Scientific Literature | ||
| 7. | ALA4775594 | B | Selectivity ratio of IC50 for of inhibition of rat alpha-2,3-O-ST3GALI to IC50 for inhibition of human alpha-2,6-ST6GAL1 | 17 | assay format | Scientific Literature | |||
| 8. | ALA4775595 | T | Toxicity in human MDA-MB-231 cells assessed as cell survival at >60 uM relative to control | Homo sapiens | 15 | cell-based format | Scientific Literature |
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