# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4689845 | T | Multiplex assay against human fibroblast | Homo sapiens | 458 | cell-based format | EUbOPEN Chemogenomic Library | ||
2. | ALA4689846 | T | Multiplex assay against HEK293T | Homo sapiens | 458 | cell-based format | EUbOPEN Chemogenomic Library | ||
3. | ALA4689853 | T | Multiplex assay against U2OS | Homo sapiens | 458 | cell-based format | EUbOPEN Chemogenomic Library | ||
4. | ALA4725212 | T | Incucyte cell viability with HEK293T | Homo sapiens | 1,713 | cell-based format | EUbOPEN Chemogenomic Library | ||
5. | ALA4725213 | T | Incucyte cell viability with human fibroblast | Homo sapiens | 1,718 | cell-based format | EUbOPEN Chemogenomic Library | ||
6. | ALA4725214 | T | Incucyte cell viability with U2OS | Homo sapiens | 1,712 | cell-based format | EUbOPEN Chemogenomic Library | ||
7. | ALA5050135 | B | Inhibition of human electron transport chain complex 1 in human NCI-H1299 cells assessed as reduction in cellular ATP level measured after 24 hrs by CellTiter-Glo assay | Homo sapiens | 42 | cell-based format | Scientific Literature | ||
8. | ALA5050141 | P | Lipophilicity, logD of compound | 35 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA5050142 | A | Metabolic stability in rat hepatocyte assessed as maximum bioavailability measured up to 90 mins by LC-MS/MS analysis | Rattus norvegicus | 9 | organism-based format | Scientific Literature | ||
10. | ALA5050144 | B | Inhibition of mouse electron transport chain complex 1 assessed as reduction in cellular ATP measured after 24 hrs by celltiter-glo assay | Mus musculus | 2 | assay format | Scientific Literature | ||
11. | ALA5050145 | B | Inhibition of rat electron transport chain complex 1 assessed as reduction in cellular ATP measured after 24 hrs by celltiter-glo assay | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
12. | ALA5050146 | B | Inhibition of dog electron transport chain complex 1 assessed as reduction in cellular ATP measured after 24 hrs by celltiter-glo assay | Canis lupus familiaris | 2 | assay format | Scientific Literature | ||
13. | ALA5050147 | P | Solubility of the compound at pH 6.5 | 2 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA5050148 | A | Apparent permeability across apical to basolateral side in human Caco2 cells assessed as drug recovery at 2 uM and measured for 2 hrs by LC-MS/MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA5050149 | A | Efflux ratio of apparent permeability across basolateral to apical side over apical to basolateral side in human Caco2 cells at 2 uM incubated for 2 hrs by LC-MS/MS analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA5050150 | A | Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
17. | ALA5050151 | A | Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
18. | ALA5050152 | A | Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
19. | ALA5050153 | A | Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
20. | ALA5050154 | A | Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature |