# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4727274 | A | Agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assay | Homo sapiens | 2 | ALA4725299 | cell-based format | Scientific Literature | |
2. | ALA4727278 | A | Agonist activity at human NMUR1 expressed in CHO cells at 10 nM by calcium mobilization assay relative to control | Homo sapiens | 3 | ALA4725299 | cell-based format | Scientific Literature | |
3. | ALA4727280 | A | Agonist activity at human NMUR1 expressed in CHO cells assessed as intrinsic activity at 10^-6 to 10^-12 M by calcium mobilization assay relative to control | Homo sapiens | 2 | ALA4725299 | cell-based format | Scientific Literature | |
4. | ALA4727282 | A | Stability of the compound in 25% human serum assessed as intact residual rate at 50 uM incubated for 180 mins at 37 degreeC | Homo sapiens | 3 | ALA4725299 | cell-free format | Scientific Literature | |
5. | ALA4727283 | A | Drug metabolism in 25% human serum assessed as M1 metabolite formation at 50 uM incubated for 180 mins at 37 degreeC by HPLC analysis | Homo sapiens | 1 | ALA4725299 | cell-free format | Scientific Literature | |
6. | ALA4727284 | A | Drug metabolism in 25% human serum assessed as M2 metabolite formation at 50 uM incubated for 180 mins at 37 degreeC by HPLC analysis | Homo sapiens | 1 | ALA4725299 | cell-free format | Scientific Literature | |
7. | ALA4727287 | A | Agonist activity at human NMUR2 expressed in CHO cells by calcium mobilization assay | Homo sapiens | 1 | ALA4725299 | cell-based format | Scientific Literature | |
8. | ALA4727288 | A | Selectivity index, ratio of EC50 for agonist activity for human NMUR2 expressed in CHO cells to EC50 for agonist activity for human NMUR1 expressed in CHO cells by calcium mobilization assay | Homo sapiens | 2 | ALA4725299 | cell-based format | Scientific Literature |