#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4770538	ADME	Metabolic stability in rat liver microsomes assessed as parent compound remaining at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 30 mins	Rattus norvegicus	21	ALA4765335	microsome format	Scientific Literature
2.	ALA4770539	Binding	Displacement of [3H]-5-CT from human 5-HT7R expressed in human HEK293 cells assessed as inhibitory constant incubated for 60 mins by radioligand binding assay	Homo sapiens	22	ALA4765335	cell-based format	Scientific Literature
3.	ALA4770540	Binding	Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in human HEK293 cells assessed as inhibitory constant incubated for 60 mins by radioligand binding assay	Homo sapiens	22	ALA4765335	cell-based format	Scientific Literature
4.	ALA4770541	ADME	Metabolic stability in rat liver microsomes assessed as half life at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 30 mins	Rattus norvegicus	10	ALA4765335	microsome format	Scientific Literature
5.	ALA4770542	ADME	Metabolic stability in rat liver microsomes assessed as apparent intrinsic clearance at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 30 mins	Rattus norvegicus	10	ALA4765335	microsome format	Scientific Literature
6.	ALA4770543	ADME	Metabolic stability in rat hepatocytes assessed as half life at 10 uM measured up to 120 mins	Rattus norvegicus	10	ALA4765335	cell-based format	Scientific Literature
7.	ALA4770544	ADME	Protein binding in human serum albumin assessed as unbound fraction at 10 uM by TRANSIL assay	Homo sapiens	10	ALA4765335	single protein format	Scientific Literature
8.	ALA4770545	ADME	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	Homo sapiens	3	ALA4765335	cell-based format	Scientific Literature
9.	ALA4770546	ADME	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	Homo sapiens	3	ALA4765335	cell-based format	Scientific Literature
10.	ALA4770547	ADME	Cytotoxicity against human SH-SY5Y cells after 48 hrs by MTT assay	Homo sapiens	3	ALA4765335	cell-based format	Scientific Literature
11.	ALA4770548	Binding	Inhibition of human ERG expressed in CHO cells by patch clamp method	Homo sapiens	4	ALA4765335	cell-based format	Scientific Literature
12.	ALA4770549	ADME	Inhibition of human Nav1.5 expressed in HEK293T cells at 0.1 to 10 Hz frequency at -120 mV holding potential by whole cell patch clamp electrophysiology assay	Homo sapiens	3	ALA4765335	cell-based format	Scientific Literature
13.	ALA4770550	Binding	Agonist activity at 5HT7 receptor in C57BL/6 mouse hippocampal neurons assessed as reversal of DHPG induced mGluR-dependent long-term depression by measuring excitatory postsynaptic current at -70 mV holding potential at 100 nM pretreated with DHPG for 5 mins after DHPG washout compound addition measured after 40 mins by whole cell patch clamp assay (Rvb = 67.7 +/- 8 %)	Mus musculus	2	ALA4765335	tissue-based format	Scientific Literature
14.	ALA4770551	Functional	Effect on behavioral changes in Fmr1 KO C57BL/6J mouse assessed as reduction in digging behavior under nesting out condition at 3 mg/kg, ip after 30 mins by nesting removal test	Mus musculus	1	ALA4765335	organism-based format	Scientific Literature
15.	ALA4770552	Functional	Effect on locomotor activity in Fmr1 KO C57BL/6J mouse at 3 mg/kg, ip measured after 30 mins under nesting out condition	Mus musculus	1	ALA4765335	organism-based format	Scientific Literature
16.	ALA4770553	Functional	Effect on locomotor activity in wild type C57BL/6J mouse at 3 mg/kg, ip measured after 30 mins under nesting out condition	Mus musculus	1	ALA4765335	organism-based format	Scientific Literature