| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4670944 | B | Inhibition of HER2-A775_G776insYVMA mutant (unknown origin) expressed in mouse BaF3 cells assessed as reduction in HER2 induced cell viability after 96 hrs by CellTiter-Glo assay | Homo sapiens | 41 | ALA4665812 | cell-based format | Scientific Literature | |
| 2. | ALA4670945 | B | Inhibition of HER2-G776delinsVC mutant (unknown origin) expressed in human H1781 cells assessed as reduction in HER2 induced cell viability after 96 hrs by CellTiter-Glo assay | Homo sapiens | 41 | ALA4665812 | cell-based format | Scientific Literature | |
| 3. | ALA4670946 | B | Inhibition of C-terminal His6-tagged HER2-A775_G776insYVMA mutant (703 to 1029 residues) (unknown origin) expressed in Sf9 insect cells using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 40 mins in presence of XL665-labeled streptavidin by HTRF assay | Homo sapiens | 41 | ALA4665812 | cell-based format | Scientific Literature | |
| 4. | ALA4670947 | B | Inhibition of C-terminal His6-tagged HER2 (703 to 1029 residues) (unknown origin) expressed in Sf9 insect cells using TK as substrate preincubated for 30 mins followed by substrate addition and measured after 60 mins in presence of XL665-labeled streptavidin by HTRF assay | Homo sapiens | 41 | ALA4665812 | cell-based format | Scientific Literature | |
| 5. | ALA5143769 | B | Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) | Homo sapiens | 36 | ALA5143505 | single protein format | Scientific Literature |
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