# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4685798 | B | Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit at 50 uM using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substrate addition and measured for 10 mins by bioluminescent assay relative to control | Homo sapiens | 26 | ALA4680218 | single protein format | Scientific Literature | |
2. | ALA4685799 | B | Inhibition of chymotrypsin-like activity of human 20S proteasome beta5 subunit using Suc-LLVY-Glo as substrate incubated for 2 hrs followed by substrate addition and measured for 10 mins by bioluminescent assay | Homo sapiens | 26 | ALA4680218 | single protein format | Scientific Literature | |
3. | ALA4685809 | F | Cytotoxicity against human A-375 cells assessed as reduction in cell viability after 72 hrs by Cell Titer-Glo assay | Homo sapiens | 4 | ALA4680218 | cell-based format | Scientific Literature | |
4. | ALA4685810 | F | Cytotoxicity against human BGC-823 cells assessed as reduction in cell viability after 72 hrs by Cell Titer-Glo assay | Homo sapiens | 4 | ALA4680218 | cell-based format | Scientific Literature | |
5. | ALA4685811 | F | Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by Cell Titer-Glo assay | Homo sapiens | 4 | ALA4680218 | cell-based format | Scientific Literature | |
6. | ALA4685812 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by Cell Titer-Glo assay | Homo sapiens | 4 | ALA4680218 | cell-based format | Scientific Literature | |
7. | ALA4685813 | F | Cytotoxicity against human PC3M1E8 cells assessed as reduction in cell viability after 72 hrs by Cell Titer-Glo assay | Homo sapiens | 4 | ALA4680218 | cell-based format | Scientific Literature | |
8. | ALA4685814 | F | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 72 hrs by Cell Titer-Glo assay | Homo sapiens | 4 | ALA4680218 | cell-based format | Scientific Literature | |
9. | ALA4685815 | A | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability after 72 hrs by Cell Titer-Glo assay | Homo sapiens | 4 | ALA4680218 | cell-based format | Scientific Literature | |
10. | ALA4685816 | F | Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by Cell Titer-Glo assay | Homo sapiens | 4 | ALA4680218 | cell-based format | Scientific Literature | |
11. | ALA4685817 | F | Cell cycle arrest in human HCT-116 cells assessed as accumulation at G1 phase at 1 uM after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 29%) | Homo sapiens | 4 | ALA4680218 | cell-based format | Scientific Literature | |
12. | ALA4685818 | F | Cell cycle arrest in human HCT-116 cells assessed as accumulation at S phase at 1 uM after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 50%) | Homo sapiens | 4 | ALA4680218 | cell-based format | Scientific Literature | |
13. | ALA4685819 | F | Cell cycle arrest in human HCT-116 cells assessed as accumulation at G2/M phase at 1 uM after 24 hrs by propidium iodide staining based flow cytometric analysis (Rvb = 21%) | Homo sapiens | 4 | ALA4680218 | cell-based format | Scientific Literature | |
14. | ALA4685839 | A | Inhibition of caspase-like activity of human 20S proteasome beta 1 subunit at 50 uM using Z-nLPnLD-Glo as substrate incubated for 2 hrs followed by substrate addition and measured for 10 mins by bioluminescent assay | Homo sapiens | 25 | ALA4680218 | single protein format | Scientific Literature | |
15. | ALA4685840 | A | Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit using Z-LRR-Glo as substrate at 50 uM incubated for 2 hrs followed by substrate addition and measured for 10 mins by bioluminescent assay | Homo sapiens | 25 | ALA4680218 | single protein format | Scientific Literature |