#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4767464	B	Inhibition of recombinant human PAK4 kinase domain (300 to 591 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate using serine/threonine-20 peptide as substrate at 50 uM incubated for 60 mins in presence of ATP by FRET based Z'-LYTE assay	Homo sapiens	14		assay format	Scientific Literature
2.	ALA4767465	B	Inhibition of recombinant human PAK4 kinase domain (300 to 591 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate using serine/threonine-20 peptide as substrate at 5 uM incubated for 60 mins in presence of ATP by FRET based Z'-LYTE assay	Homo sapiens	14		assay format	Scientific Literature
3.	ALA4767466	B	Inhibition of recombinant human PAK4 kinase domain (300 to 591 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition rate using serine/threonine-20 peptide as substrate at 0.5 uM incubated for 60 mins in presence of ATP by FRET based Z'-LYTE assay	Homo sapiens	14		assay format	Scientific Literature
4.	ALA4767467	P	Chemical stability of the compound in pH 7.4 PBS buffer assessed as compound remaining measured after 2 hrs by HPLC analysis		12		small-molecule physicochemical format	Scientific Literature
5.	ALA4767468	U	Chemical stability of the compound in pH 1.2 simulated gastric fluid buffer assessed as compound remaining measured after 2 hrs by HPLC analysis		12		small-molecule physicochemical format	Scientific Literature
6.	ALA4767469	U	Chemical stability of the compound in pH 6.8 simulated intestinal fluid assessed as compound remaining measured after 2 hrs by HPLC analysis		12		small-molecule physicochemical format	Scientific Literature
7.	ALA4767470	A	Stability of the compound in human plasma assessed as compound remaining measured within 120 mins at 37 degC by HPLC analysis	Homo sapiens	13		cell-free format	Scientific Literature
8.	ALA4767471	A	Prodrug conversion in human plasma assessed as release of active metabolite (R)-(6-chloro-4-(5-cyclopropyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)(3-methylpiperazin-1-yl)methanone hydrochloride measured within 120 mins at 37 degC by HPLC analysis	Homo sapiens	12		cell-free format	Scientific Literature
9.	ALA4767472	A	Stability of the compound in rat liver S9 fraction assessed as compound remaining measured after 60 mins at 37 degC by LC-MS/MS analysis	Rattus norvegicus	13		subcellular format	Scientific Literature
10.	ALA4767473	A	Prodrug conversion in rat liver S9 fraction assessed as release of active metabolite (R)-(6-chloro-4-(5-cyclopropyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)(3-methylpiperazin-1-yl)methanone hydrochloride measured after 60 mins at 37 degC by LC-MS/MS analysis	Rattus norvegicus	12		subcellular format	Scientific Literature
11.	ALA4767481	A	AUC in Wistar rat assessed as (R)-(6-chloro-4-(5-cyclopropyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)(3-methylpiperazin-1-yl)methanone hydrochloride at 12.43 mg/kg, po measured upto 24 hrs by LC/MS/MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
12.	ALA4767482	A	AUC (0 to infinity) in Wistar rat assessed as (R)-(6-chloro-4-(5-cyclopropyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)(3-methylpiperazin-1-yl)methanone hydrochloride at 12.43 mg/kg, po measured upto 24 hrs by LC/MS/MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
13.	ALA4767483	A	Half life in Wistar rat assessed as (R)-(6-chloro-4-(5-cyclopropyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)(3-methylpiperazin-1-yl)methanone hydrochloride at 12.43 mg/kg, po measured upto 24 hrs by LC/MS/MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
14.	ALA4767484	A	Tmax in Wistar rat assessed as (R)-(6-chloro-4-(5-cyclopropyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)(3-methylpiperazin-1-yl)methanone hydrochloride at 12.43 mg/kg, po measured upto 24 hrs by LC/MS/MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature
15.	ALA4767485	A	Cmax in Wistar rat assessed as (R)-(6-chloro-4-(5-cyclopropyl-1H-pyrazol-3-ylamino)quinazolin-2-yl)(3-methylpiperazin-1-yl)methanone hydrochloride at 12.43 mg/kg, po measured upto 24 hrs by LC/MS/MS analysis	Rattus norvegicus	1		organism-based format	Scientific Literature