| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4770333 | F | Antiproliferative activity against human CAPAN-1 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 2. | ALA4770334 | F | Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 3. | ALA4770335 | F | Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 4. | ALA4770336 | F | Antiproliferative activity against human HL-60 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 5. | ALA4770337 | F | Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 6. | ALA4770338 | F | Antiproliferative activity against P-gp-positive/doxorubicin-resistant human K562/4 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 10 | tissue-based format | Scientific Literature | ||
| 7. | ALA4770339 | F | Antiproliferative activity against human HCT-116 cells with inactivated p53 gene assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 8. | ALA4770340 | A | Cytotoxicity against human TERT-RPE1 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | cell-based format | Scientific Literature | ||
| 9. | ALA4770341 | U | Selectivity index, ratio of IC50 for human TERT-RPE1 cells to IC50 for human CAPAN-1 cells | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 10. | ALA4770342 | F | Resistance index, ratio of IC50 for human P-gp-positive/Doxorubicin-resistant K562/4 cells to IC50 for human K562 cells | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 11. | ALA4770343 | F | Resistance index, ratio of IC50 for human HCT-116 cells to IC50 for human HCT-116 cells with inactivated p53 | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 12. | ALA4770344 | B | Binding affinity to calf thymus double stranded DNA at 10 uM measured after 5 mins by flourescence spectroscopy method | Bos taurus | 4 | tissue-based format | Scientific Literature | ||
| 13. | ALA4770345 | B | Binding affinity to calf thymus DNA assessed as DNA intercalation by measuring decrease of negative DNA band at 245 nm at 50 uM by circular dichroism spectral analysis | Bos taurus | 4 | tissue-based format | Scientific Literature | ||
| 14. | ALA4770346 | B | Binding affinity to calf thymus DNA assessed as binding constant by scatchard plot analysis | Bos taurus | 4 | tissue-based format | Scientific Literature | ||
| 15. | ALA4770347 | B | Binding affinity to calf thymus DNA assessed as dissociation constant by scatchard plot analysis | Bos taurus | 4 | tissue-based format | Scientific Literature | ||
| 16. | ALA4770348 | B | Binding affinity to calf thymus DNA assessed as stoichiometry ratio of compound-DNA complex formation by scatchard plot analysis | Bos taurus | 4 | tissue-based format | Scientific Literature | ||
| 17. | ALA4770349 | B | Inhibition of human topoisomerase 1-mediated relaxation of supercoiled plasmid using pBR322 plasmid as substrate at 40 uM measured after 30 mins by ethidium bromide dye based agarose gel electrophoresis method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 18. | ALA4770350 | A | Drug uptake in mouse NIH3T3 cells assessed as compound localization in nucleus at 1 uM measured after 15 mins by laser scanning microscope | Mus musculus | 3 | subcellular format | Scientific Literature | ||
| 19. | ALA4770351 | A | Drug uptake in mouse NIH3T3 cells assessed as compound localization in mitochondria at 1 uM measured after 15 mins by Mitotracker Green FM dye based laser scanning microscope | Mus musculus | 2 | mitochondrion format | Scientific Literature | ||
| 20. | ALA4770352 | A | Drug uptake in mouse NIH3T3 cells assessed as compound localization in cytoplasm at 1 uM measured after 15 mins by laser scanning microscope | Mus musculus | 2 | subcellular format | Scientific Literature |
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