# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4669975 | ADME | Substrate activity at human OATP1B3 stably expressed in HEK293 cells assessed as ratio of total to passive cellular uptake at 1 uM incubated for 5 mins by LC/MS-MS analysis | Homo sapiens | 3 | ALA4665761 | cell-based format | Scientific Literature | |
2. | ALA4669976 | ADME | Substrate activity at human OATP1B1 stably expressed in HEK293 cells assessed as ratio of total to passive cellular uptake at 1 uM incubated for 5 mins by LC/MS-MS analysis | Homo sapiens | 3 | ALA4665761 | cell-based format | Scientific Literature | |
3. | ALA4669977 | ADME | Metabolic intrinsic clearance in human hepatocytes assessed per million cells incubated for 2 hrs | Homo sapiens | 5 | ALA4665761 | cell-based format | Scientific Literature | |
4. | ALA4669978 | Physicochemical | Octanol-water partition coefficient, logD of compound at pH 7.4 at 0.5 to 2 mg incubated for 1 hr by HPLC based shake-flask method | 5 | ALA4665761 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4669979 | ADME | Apparent permeability in MCDKII-LE cells at 2 uM incubated for 30 mins | Canis lupus familiaris | 9 | ALA4665761 | cell-based format | Scientific Literature | |
6. | ALA4669980 | Binding | Inhibition of recombinant human ACC2 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assay | Homo sapiens | 9 | ALA4665761 | single protein format | Scientific Literature | |
7. | ALA4669981 | Binding | Inhibition of recombinant human ACC1 using acetyl coA as substrate incubated for 1 hr by transcreener fluorescence polarization assay | Homo sapiens | 9 | ALA4665761 | single protein format | Scientific Literature |