# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4677633 | B | Inhibition of recombinant human ULK1 (1-649) expressed in Sf9 cells using myelin basic protein as substrate by ADP-glo assay | Homo sapiens | 26 | ALA4673296 | cell-based format | Scientific Literature | |
2. | ALA4677634 | B | Inhibition of ULK1 (unknown origin) expressed in HEK293T cells incubated for 2 hrs by NanoBRET assay | Homo sapiens | 26 | ALA4673296 | cell-based format | Scientific Literature | |
3. | ALA4677635 | B | Inhibition of recombinant human ULK2 (1 to 478 residues) expressed in Sf9 cells using myelin basic protein as substrate by ADP-glo assay | Homo sapiens | 7 | ALA4673296 | cell-based format | Scientific Literature | |
4. | ALA4677637 | B | Inhibition of ULK2 (unknown origin) expressed in HEK293T cells incubated for 2 hrs by NanoBRET assay | Homo sapiens | 7 | ALA4673296 | cell-based format | Scientific Literature | |
5. | ALA4677638 | A | Apparent permeability of the compound across apical side to basolateral side in human Caco2 cells | Homo sapiens | 8 | ALA4673296 | cell-based format | Scientific Literature | |
6. | ALA4677639 | A | Apparent permeability of the compound across basolateral side to apical side in human Caco2 cells | Homo sapiens | 8 | ALA4673296 | cell-based format | Scientific Literature | |
7. | ALA4677640 | A | Efflux ratio of apparent permeability from basolateral side to apical side over apical side to basolateral side in human Caco2 cells | Homo sapiens | 8 | ALA4673296 | cell-based format | Scientific Literature | |
8. | ALA4677641 | B | Inhibition of Myc-tagged ULK1 (unknown origin) expressed in HEK293T cells cotransfected with wild-type Flag tagged Beclin-1 assessed as decrease in pBeclin1 Ser15 at 10 uM measured after 1 hr by Western blot analysis | Homo sapiens | 5 | ALA4673296 | cell-based format | Scientific Literature | |
9. | ALA4677643 | B | Inhibition of Myc-tagged ULK1 (unknown origin) expressed in HEK293T cells cotransfected with wild-type Flag tagged Vps34 assessed as decrease in pVPS34 Ser249 at 10 uM measured after 1 hr by Western blot analysis relative to control | Homo sapiens | 7 | ALA4673296 | cell-based format | Scientific Literature |