Antitumour activity against human HCT-116 cells xenografted in ip dosed BALB/c nude mouse assessed as tumour growth inhibition administered once for every 7 days for 14 days
Antitumour activity against human HCT-116 cells xenografted in BALB/c nude mouse assessed as tumour growth inhibition at 11.1 mg/kg, ip administered once for every 7 days for 14 days relative to control
Antitumour activity against human HCT-116 cells xenografted in BALB/c nude mouse assessed as tumour growth inhibition at 22.2 mg/kg, ip administered once for every 7 days for 14 days relative to control
Antitumour activity against human HCT-116 cells xenografted in BALB/c nude mouse assessed as tumour growth inhibition at 5.55 mg/kg, ip administered once for every 7 days for 14 days relative to control
Toxicity in BALB/c nude mouse xenografted with human HCT-116 cells assessed as reduction in body weight at 22.2 mg/kg, ip administered once for every 7 days for 14 days relative to control
Toxicity in BALB/c nude mouse xenografted with human HCT-116 cells assessed as reduction in body weight at 11.1 mg/kg, ip administered once for every 7 days for 14 days relative to control
Toxicity in BALB/c nude mouse xenografted with human HCT-116 cells assessed as reduction in body weight at 5.5 mg/kg, ip administered once for every 7 days for 14 days relative to control
Toxicity in BALB/c nude mouse xenografted with human HCT-116 cells assessed as concentrated nucleus in liver at 11.17 mg/kg, ip administered once for every 7 days for 14 days by H and E staining based assay
Toxicity in BALB/c nude mouse xenografted with human HCT-116 cells assessed as necrosis in liver at 11.17 mg/kg, ip administered once for every 7 days for 14 days by H and E staining based assay
Toxicity in BALB/c nude mouse xenografted with human HCT-116 cells assessed as disordered myocardial fiber in heart at 11.17 mg/kg, ip administered once for every 7 days for 14 days by H and E staining based assay
Toxicity in BALB/c nude mouse xenografted with human HCT-116 cells assessed as inflammatory cell invasion in heart at 11.17 mg/kg, ip administered once for every 7 days for 14 days by H and E staining based assay