| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4770179 | Binding | Disruption of cell membrane integrity in Staphylococcus aureus at 2 uM irradiated with 6J/cm2 light followed by compound exposure for 10 mins by FL-4L/propidium iodide Live/dead staining based laser confocal microscopic analysis | Staphylococcus aureus | 2 | ALA4765326 | subcellular format | Scientific Literature | |
| 2. | ALA4770180 | Functional | Induction of singlet oxygen generation in DPBF solution assessed as singlet oxygen quantum yield irradiated with 80 mW/cm2 light by DPBF-based assay | 12 | ALA4765326 | assay format | Scientific Literature | ||
| 3. | ALA4770181 | Physicochemical | Octanol-water partition coefficient, logP of compound incubated for 24 hrs under shaking condition | 14 | ALA4765326 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA4770182 | Functional | Photodynamic antibacterial activity against Staphylococcus aureus assessed as bacterial eradication preincubated for 20 mins in dark condition followed by 18 J/cm2 LED light irradiation and measured after 18 hrs by broth microdilution method | Staphylococcus aureus | 12 | ALA4765326 | organism-based format | Scientific Literature | |
| 5. | ALA4770183 | Functional | Photodynamic antibacterial activity against Escherichia coli assessed as bacterial eradication preincubated for 20 mins in dark condition followed by 18 J/cm2 LED light irradiation and measured after 18 hrs by broth microdilution method | Escherichia coli | 12 | ALA4765326 | organism-based format | Scientific Literature | |
| 6. | ALA4770184 | Functional | Photodynamic antifungal activity against Candida albicans assessed as fungal eradication preincubated for 20 mins in dark condition followed by 18 J/cm2 LED light irradiation and measured after 18 hrs by broth microdilution method | Candida albicans | 12 | ALA4765326 | organism-based format | Scientific Literature | |
| 7. | ALA4770185 | Functional | Photodynamic antibacterial activity against methicillin resistant Staphylococcus aureus assessed as bacterial eradication preincubated for 20 mins in dark condition followed by 18 J/cm2 LED light irradiation and measured after 18 hrs by broth microdilution method | Staphylococcus aureus | 12 | ALA4765326 | organism-based format | Scientific Literature | |
| 8. | ALA4770186 | Functional | Photodynamic antimicrobial activity against Staphylococcus aureus preincubated for 10 mins in dark followed by irradiation with 6J/cm2 light and measured after incubation for 36 to 48 hrs | Staphylococcus aureus | 1 | ALA4765326 | organism-based format | Scientific Literature | |
| 9. | ALA4770187 | Functional | Photodynamic antimicrobial activity against Escherichia coli preincubated for 10 mins in dark followed by irradiation with 6J/cm2 light and measured after incubation for 36 to 48 hrs | Escherichia coli | 1 | ALA4765326 | organism-based format | Scientific Literature | |
| 10. | ALA4770188 | Functional | Photodynamic antimicrobial activity against Candida albicans preincubated for 10 mins in dark followed by irradiation with 9J/cm2 light and measured after incubation for 36 to 48 hrs | Candida albicans | 1 | ALA4765326 | organism-based format | Scientific Literature | |
| 11. | ALA4770189 | Functional | Photodynamic antimicrobial activity against methicillin resistant Staphylococcus aureus preincubated for 10 mins in dark followed by irradiation with 6J/cm2 light and measured after incubation for 36 to 48 hrs | Staphylococcus aureus | 1 | ALA4765326 | organism-based format | Scientific Literature | |
| 12. | ALA4770190 | Functional | Antimicrobial activity against Staphylococcus aureus incubated for 36 to 48 hrs under dark conditions | Staphylococcus aureus | 1 | ALA4765326 | organism-based format | Scientific Literature | |
| 13. | ALA4770191 | Functional | Antimicrobial activity against Escherichia coli incubated for 36 to 48 hrs under dark conditions | Escherichia coli | 1 | ALA4765326 | organism-based format | Scientific Literature | |
| 14. | ALA4770192 | Functional | Antimicrobial activity against Candida albicans incubated for 36 to 48 hrs under dark conditions | Candida albicans | 1 | ALA4765326 | organism-based format | Scientific Literature | |
| 15. | ALA4770193 | Functional | Antimicrobial activity against methicillin resistant Staphylococcus aureus incubated for 36 to 48 hrs under dark conditions | Staphylococcus aureus | 1 | ALA4765326 | organism-based format | Scientific Literature | |
| 16. | ALA4770194 | Binding | Binding affinity to Staphylococcus aureus cell wall assessed as bound fraction at 25 uM measured after 3 to 10 mins | Staphylococcus aureus | 3 | ALA4765326 | assay format | Scientific Literature | |
| 17. | ALA4770195 | Binding | Binding affinity to Escherichia coli cell wall assessed as bound fraction at 25 uM measured after 3 to 10 mins | Escherichia coli | 3 | ALA4765326 | assay format | Scientific Literature | |
| 18. | ALA4770196 | Binding | Binding affinity to Candida albicans cell wall assessed as bound fraction at 25 uM measured after 3 to 10 mins | Candida albicans | 3 | ALA4765326 | assay format | Scientific Literature | |
| 19. | ALA4770198 | Binding | Binding affinity to Staphylococcus aureus cell wall at 50 uM preincubated with 12.5 to 50 mM Ca2+ for 30 mins followed by incubation with compound for 30 mins | Staphylococcus aureus | 3 | ALA4765326 | assay format | Scientific Literature | |
| 20. | ALA4770199 | Binding | Binding affinity to Escherichia coli cell wall at 50 uM preincubated with 12.5 to 50 mM Ca2+ for 30 mins followed by incubation with compound for 30 mins | Escherichia coli | 3 | ALA4765326 | assay format | Scientific Literature |
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