| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4729413 | B | Inhibition of human recombinant HDAC1 using ZMAL (Z-Lys(Ac)-AMC) fluorogenic substrate incubated for 90 mins by fluorescence based assay | Homo sapiens | 17 | ALA4725369 | single protein format | Scientific Literature | |
| 2. | ALA4729414 | B | Inhibition of human recombinant HDAC6 using ZMAL (Z-Lys(Ac)-AMC) fluorogenic substrate incubated for 90 mins by fluorescence based assay | Homo sapiens | 17 | ALA4725369 | single protein format | Scientific Literature | |
| 3. | ALA4729415 | B | Selectivity index, ratio of IC50 for inhibition of human recombinant HDAC1 to IC50 for inhibition of human recombinant HDAC6 | Homo sapiens | 17 | ALA4725369 | assay format | Scientific Literature | |
| 4. | ALA4729416 | B | Inhibition of human recombinant HDAC2 using ZMAL (Z-Lys(Ac)-AMC) fluorogenic substrate incubated for 90 mins by fluorescence based assay | Homo sapiens | 1 | ALA4725369 | single protein format | Scientific Literature | |
| 5. | ALA4729417 | B | Selectivity index, ratio of IC50 for inhibition of human recombinant HDAC2 to IC50 for inhibition of human recombinant HDAC6 | Homo sapiens | 1 | ALA4725369 | assay format | Scientific Literature | |
| 6. | ALA4729418 | B | Inhibition of human recombinant HDAC3 using ZMAL (Z-Lys(Ac)-AMC) fluorogenic substrate incubated for 90 mins by fluorescence based assay | Homo sapiens | 1 | ALA4725369 | single protein format | Scientific Literature | |
| 7. | ALA4729419 | B | Selectivity index, ratio of IC50 for inhibition of human recombinant HDAC3 to IC50 for inhibition of human recombinant HDAC6 | Homo sapiens | 1 | ALA4725369 | assay format | Scientific Literature | |
| 8. | ALA4729420 | B | Inhibition of human recombinant HDAC4 using Boc-Lys-(epsilon-Tfa)-AMC fluorogenic substrate incubated for 90 mins by fluorescence based assay | Homo sapiens | 2 | ALA4725369 | single protein format | Scientific Literature | |
| 9. | ALA4729421 | B | Selectivity index, ratio of IC50 for inhibition of human recombinant HDAC4 to IC50 for inhibition of human recombinant HDAC6 | Homo sapiens | 1 | ALA4725369 | assay format | Scientific Literature | |
| 10. | ALA4729422 | B | Inhibition of human recombinant HDAC8 using Boc-Lys-(epsilon-Tfa)-AMC fluorogenic substrate incubated for 90 mins by fluorescence based assay | Homo sapiens | 1 | ALA4725369 | single protein format | Scientific Literature | |
| 11. | ALA4729423 | B | Selectivity index, ratio of IC50 for inhibition of human recombinant HDAC8 to IC50 for inhibition of human recombinant HDAC6 | Homo sapiens | 2 | ALA4725369 | assay format | Scientific Literature | |
| 12. | ALA4729424 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 1 | ALA4725369 | microsome format | Scientific Literature | |
| 13. | ALA4729425 | A | Intrinsic clearance in mouse liver microsomes | Mus musculus | 1 | ALA4725369 | microsome format | Scientific Literature | |
| 14. | ALA4729426 | B | Inhibition of HDAC6 in human HL60 cells assessed as induction of alpha-tubulin acetylation at 2.5 to 5 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA4725369 | cell-based format | Scientific Literature | |
| 15. | ALA4729427 | B | Inhibition of class-1 HDAC in human HL60 cells assessed as induction of histone H3 acetylation at 2.5 to 5 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | ALA4725369 | cell-based format | Scientific Literature | |
| 16. | ALA4729428 | A | Cytotoxicity in human TALL-1 cells assessed as reduction in cell viability incubated for 72 hrs by cell-Titer-Glo luminescent cell viability assay | Homo sapiens | 1 | ALA4725369 | cell-based format | Scientific Literature | |
| 17. | ALA4729429 | A | Cytotoxicity in human CCRF-HSB-2 cells assessed as reduction in cell viability incubated for 72 hrs by cell-Titer-Glo luminescent cell viability assay | Homo sapiens | 1 | ALA4725369 | cell-based format | Scientific Literature | |
| 18. | ALA4729430 | A | Cytotoxicity in human MOLT-4 cells assessed as reduction in cell viability incubated for 72 hrs by cell-Titer-Glo luminescent cell viability assay | Homo sapiens | 1 | ALA4725369 | cell-based format | Scientific Literature | |
| 19. | ALA4729431 | A | Cytotoxicity in human Jurkat cells assessed as reduction in cell viability incubated for 72 hrs by cell-Titer-Glo luminescent cell viability assay | Homo sapiens | 1 | ALA4725369 | cell-based format | Scientific Literature | |
| 20. | ALA4729432 | A | Cytotoxicity in human HL-60 cells assessed as reduction in cell viability incubated for 72 hrs by cell-Titer-Glo luminescent cell viability assay | Homo sapiens | 1 | ALA4725369 | cell-based format | Scientific Literature |
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