# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4709424 | Functional | Antiproliferative activity against human COLO357 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA4706539 | cell-based format | Scientific Literature | |
2. | ALA4709425 | Functional | Antiproliferative activity against human SW-620 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA4706539 | cell-based format | Scientific Literature | |
3. | ALA4709426 | ADME | Cytotoxicity against human HEK293 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA4706539 | cell-based format | Scientific Literature | |
4. | ALA4709427 | Functional | Antiproliferative activity against human Raji cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 18 | ALA4706539 | cell-based format | Scientific Literature | |
5. | ALA4709428 | ADME | Cytotoxicity against human HaCat cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 10 | ALA4706539 | cell-based format | Scientific Literature | |
6. | ALA4709429 | Functional | Antiproliferative activity against human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 10 | ALA4706539 | cell-based format | Scientific Literature | |
7. | ALA4709430 | Functional | Antiproliferative activity against human PANC-1 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay | Homo sapiens | 10 | ALA4706539 | cell-based format | Scientific Literature | |
8. | ALA4709431 | Functional | Induction of cell cycle arrest in human COLO357 cells assessed as accumulation at G2/M phase at 5 nM incubated for 48 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 13 %) | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
9. | ALA4709432 | Functional | Induction of cell cycle arrest in human COLO357 cells assessed as accumulation at G1 phase at 5 nM incubated for 48 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 72 %) | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
10. | ALA4709433 | Functional | Induction of cell cycle arrest in human COLO357 cells assessed as accumulation at apoptotic phase at 5 nM incubated for 48 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 1.3 %) | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
11. | ALA4709434 | Functional | Induction of cell cycle arrest in human SW-620 cells assessed as accumulation at G2/M phase at 5 nM incubated for 48 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 16 %) | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
12. | ALA4709435 | Functional | Induction of cell cycle arrest in human SW-620 cells assessed as accumulation at G1 phase at 5 nM incubated for 48 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 65 %) | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
13. | ALA4709436 | Functional | Induction of cell cycle arrest in human SW-620 cells assessed as accumulation at apoptotic phase at 5 nM incubated for 48 hrs by RNase/PI staining based flow cytometry analysis (Rvb = 0.8 %) | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
14. | ALA4709437 | Binding | Inhibition of tubulin assembly in human COLO357 cells assessed as disruption of mitotic spindle at 5 nM incubated for 24 hrs by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
15. | ALA4709438 | Binding | Inhibition of tubulin assembly in human COLO357 cells assessed as induction of tubulin dissipation at 5 nM incubated for 24 hrs by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
16. | ALA4709439 | Binding | Inhibition of tubulin assembly in human COLO357 cells assessed as induction of chromosome disturbance at 5 nM incubated for 24 hrs by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
17. | ALA4709440 | Binding | Inhibition of tubulin assembly in human SW-620 cells assessed as disruption of mitotic spindle at 5 nM incubated for 24 hrs by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
18. | ALA4709441 | Binding | Inhibition of tubulin assembly in human SW-620 cells assessed as induction of tubulin dissipation at 5 nM incubated for 24 hrs by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
19. | ALA4709442 | Binding | Inhibition of tubulin assembly in human SW-620 cells assessed as induction of chromosome disturbance at 5 nM incubated for 24 hrs by Hoechst 33342 staining based confocal microscopic analysis | Homo sapiens | 2 | ALA4706539 | cell-based format | Scientific Literature | |
20. | ALA4709443 | Binding | Inhibition of lamb brain tubulin polymerization assessed as reduction in microtubule assembly at 0.5 to 5 uM incubated for 40 mins at 4 degreeC by spectrophotometric analysis relative to control | Ovis aries | 1 | ALA4706539 | tissue-based format | Scientific Literature |