| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4769103 | B | Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measured after 1 hr by TR-FRET assay | Homo sapiens | 21 | single protein format | Scientific Literature | ||
| 2. | ALA4769105 | B | Inhibition of recombinant human His6-tagged AMPK alpha2 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measured after 1 hr by TR-FRET assay | Homo sapiens | 20 | single protein format | Scientific Literature | ||
| 3. | ALA4769107 | B | Inhibition of tracer 236 binding to recombinant human N-terminal GST-tagged full length KDR (790 to 1356 residues) expressed in baculovirus expression system incubated for 1 hr by Lanthascreen assay | Homo sapiens | 12 | assay format | Scientific Literature | ||
| 4. | ALA4769109 | B | Inhibition of AMPK in human K562 cells assessed as p-ACC (Ser79) level at 5 uM in glucose free medium and in presence of 2-Deoxy-D-glucose measured after 3 hrs by ELISA relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA4769110 | B | Inhibition of AMPK in human K562 cells assessed as p-ACC (Ser79) level at 50 uM in glucose free medium and in presence of 2-Deoxy-D-glucose measured after 3 hrs by ELISA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4769114 | A | Cytotoxicity against human K562 cells assessed as reduction in cell viability at 50 uM incubated for 72 hrs by MTS assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4769116 | A | Cytotoxicity against human K562 cells assessed as reduction in cell viability at 50 uM incubated for 24 hrs by cell-titer glo assay relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA4769118 | A | Cytotoxicity against human K562 cells assessed as reduction in cell viability at 50 uM incubated for 24 hrs by celltox-green assay relative to control | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 9. | ALA4769119 | B | Inhibition of wild-type human partial length AMPK alpha1 (M1 to E306 residues) expressed in bacterial expression system at 100 nM by Kinomescan method relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 10. | ALA4769120 | B | Inhibition of wild-type human partial length AMPK alpha2 (M1 to E306 residues) expressed in bacterial expression system at 100 nM by Kinomescan method relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 11. | ALA4769121 | B | Inhibition of wild-type human partial length VEGFR2 (R787 to P1253 residues) expressed in mammalian expression system at 100 nM by Kinomescan method relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 12. | ALA4769122 | B | Inhibition of wild-type human full length BTK (M1 to S659 residues) expressed in mammalian expression system at 100 nM by Kinomescan method relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 13. | ALA4769123 | B | Inhibition of wild-type human partial length CSF1R (I564 to S939 residues) expressed in bacterial expression system at 100 nM by Kinomescan method relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 14. | ALA4769124 | B | Inhibition of wild-type human partial length autoinhibited CSF1R (Y538 to S939 residues) expressed in mammalian expression system at 100 nM by Kinomescan method relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 15. | ALA4769125 | B | Inhibition of wild-type human partial length FLT1 (R781 to F1239 residues) expressed in bacterial expression system at 100 nM by Kinomescan method relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 16. | ALA4769126 | B | Inhibition of wild-type human partial length JAK1 JH2 pseudokinase domain (R537 to D855 residues) expressed in mammalian expression system at 100 nM by Kinomescan method relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 17. | ALA4769127 | B | Inhibition of wild-type human partial length autoinhibited KIT (Y545 to D952 residues) expressed in mammalian expression system at 100 nM by Kinomescan method relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 18. | ALA4769129 | A | Cytotoxicity against human K562 cells assessed as reduction in cell viability at 50 uM incubated for 48 hrs by celltox-green assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature |
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