| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4689078 | A | Cytotoxicity against mouse N2a cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA4689079 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as reduction in ATP-induced calcium influx at 5 uM incubated for 1 hr by Fura-2AM dye based spectrofluorometry relative to control | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA4689081 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as reduction in ATP-induced EtBr uptake by cells incubated for 1 hr by fluorescence based assay relative to control | Mus musculus | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA4689082 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as reduction in ATP-induced YO-PRO-1 uptake by cells incubated for 1 hr by fluorescence based assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4689083 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as reduction in ATP-induced YO-PRO-1 uptake by cells at 10 uM incubated for 1 hr by fluorescence based assay relative to control | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA4689085 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as inhibition of ATP-induced ROS production at 0.1 uM incubated for 1 hr by using H2DCF-DA probe based fluorescence assay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4689089 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as cytoprotective activity against ATP-induced cell death by measuring increase in cell viability at 1 uM incubated for 1 hr followed by ATP addition and measured after 48 hrs by MTT assay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4689096 | B | Antagonist activity at P2X7R in mouse N2a cells assessed as inhibition of ATP-induced NO production at 0.1 to 10 uM incubated for 1 hr by using DAF-FM probe based fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!