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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4835966 A Cytotoxicity against African green monkey Vero cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay Chlorocebus sabaeus 1 ALA4834434 cell-based format Scientific Literature 2. ALA4835968 B Positive allosteric modulation of C57BL/6 mouse NMDA receptor assessed as fold change in compound potentiated NMDA-induced current relative to NMDA current alone at 30 uM measured after 15 to 30 mins by patch-clamp method Mus musculus 61 ALA4834434 tissue-based format Scientific Literature 3. ALA4835982 B Positive allosteric modulation of C57BL/6 mouse NMDA receptor assessed as potentiation of NMDA-induced current in presence of saturating glutamate by patch-clamp method Mus musculus 6 ALA4834434 tissue-based format Scientific Literature 4. ALA4835983 B Positive allosteric modulation of C57BL/6 mouse NMDA receptor assessed as fold change in compound potentiated NMDA-induced current relative to NMDA current alone in presence of saturating glutamate by patch-clamp method Mus musculus 6 ALA4834434 tissue-based format Scientific Literature 5. ALA4835984 P Brain to blood partition coefficient of the compound 61 ALA4834434 tissue-based format Scientific Literature 6. ALA4835987 F Antidepressant activity in ICR mouse assessed as decrease in immobility time at 30 mg/kg, ip measured after 26 mins by forced swim test Mus musculus 5 ALA4834434 organism-based format Scientific Literature 7. ALA4835988 F Antidepressant activity in ICR mouse assessed as decrease in immobility time at 3 to 10 mg/kg, ip measured after 26 mins by forced swim test Mus musculus 4 ALA4834434 organism-based format Scientific Literature 8. ALA4835989 A Effect on locomotor activity in ICR mouse assessed as hyperlocomotion at 10 mg/kg, ip measured after 90 mins Mus musculus 5 ALA4834434 organism-based format Scientific Literature 9. ALA4835990 A Effect on locomotor activity in ICR mouse assessed as hypolocomotion at 10 mg/kg, ip measured after 90 mins Mus musculus 5 ALA4834434 organism-based format Scientific Literature 10. ALA4835991 F Antidepressant activity in ICR mouse aassessed as inhibition of apomorphine-induced climbing behaviour at 10 mg/kg, ip administered prior to APO challenge and measured after 30 mins Mus musculus 6 ALA4834434 organism-based format Scientific Literature 11. ALA4836003 A Half life in ICR mouse at 3 mg/kg, iv measured up to 24 hrs by HPLC-MS/MS analysis Mus musculus 2 ALA4834434 organism-based format Scientific Literature 12. ALA4836004 A AUC (0 to t) in ICR mouse at 3 mg/kg, iv measured up to 24 hrs by HPLC-MS/MS analysis Mus musculus 2 ALA4834434 organism-based format Scientific Literature 13. ALA4836005 A Clearance in ICR mouse at 3 mg/kg, iv measured up to 24 hrs by HPLC-MS/MS analysis Mus musculus 2 ALA4834434 organism-based format Scientific Literature 14. ALA4836006 A MRT in ICR mouse at 3 mg/kg, iv measured up to 24 hrs by HPLC-MS/MS analysis Mus musculus 2 ALA4834434 organism-based format Scientific Literature 15. ALA4836007 A Volume of distribution at steady state in ICR mouse at 3 mg/kg, iv measured up to 24 hrs by HPLC-MS/MS analysis Mus musculus 2 ALA4834434 organism-based format Scientific Literature 16. ALA4836008 A Drug concentration in ICR mouse brain at 3 mg/kg, iv measured at 0.5 hrs by LC-MS/MS analysis Mus musculus 2 ALA4834434 organism-based format Scientific Literature 17. ALA4836009 A Drug concentration in ICR mouse plasma at 3 mg/kg, iv measured at 0.5 hrs by LC-MS/MS analysis Mus musculus 2 ALA4834434 organism-based format Scientific Literature 18. ALA4836010 A Ratio of drug concentration in brain to plasma in ICR mouse at 3 mg/kg, iv measured at 0.5 hrs by LC-MS/MS analysis Mus musculus 2 ALA4834434 organism-based format Scientific Literature 19. ALA4836011 A Drug concentration in ICR mouse brain at 3 mg/kg, iv measured at 2 hrs Mus musculus 2 ALA4834434 organism-based format Scientific Literature 20. ALA4836012 A Drug concentration in ICR mouse plasma at 3 mg/kg, iv measured at 2 hrs Mus musculus 2 ALA4834434 organism-based format Scientific Literature