#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4836452	Binding	Inhibition of RET wild type (unknown origin)	Homo sapiens	11	ALA4834457	single protein format	Scientific Literature
2.	ALA4836453	Binding	Inhibition of RET V804M mutant (unknown origin)	Homo sapiens	11	ALA4834457	single protein format	Scientific Literature
3.	ALA4836454	Binding	Inhibition of RET M918T mutant (unknown origin)	Homo sapiens	11	ALA4834457	single protein format	Scientific Literature
4.	ALA4836455	Functional	Antiproliferative activity against mouse KIF5B-RET BaF3 cells by cell based assay	Mus musculus	5	ALA4834457	cell-based format	Scientific Literature
5.	ALA4836456	ADME	Intrinsic clearance in mouse liver microsomes	Mus musculus	5	ALA4834457	microsome format	Scientific Literature
6.	ALA4836457	ADME	Clearance in mouse	Mus musculus	2	ALA4834457	organism-based format	Scientific Literature
7.	ALA4836458	ADME	Volume of distribution in mouse	Mus musculus	2	ALA4834457	organism-based format	Scientific Literature
8.	ALA4836459	ADME	AUC in mouse plasma at 10 mg/kg, po	Mus musculus	2	ALA4834457	organism-based format	Scientific Literature
9.	ALA4836460	ADME	Oral bioavailability in mouse	Mus musculus	2	ALA4834457	organism-based format	Scientific Literature
10.	ALA4836461	Functional	Antitumor activity against mouse KIF5B-RET BaF3 cells xenografted in nu/nu mouse assessed as tumour growth inhibition at 10 mg/kg, po qd for 10 days	Mus musculus	2	ALA4834457	organism-based format	Scientific Literature
11.	ALA4836462	Functional	Antitumor activity against mouse KIF5B-RET BaF3 cells xenografted in nu/nu mouse assessed as tumour growth inhibition at 20 mg/kg, po qd for 10 days	Mus musculus	1	ALA4834457	organism-based format	Scientific Literature
12.	ALA4836463	Toxicity	Toxicity in mouse transplanted with mouse KIF5B-RET Ba/F3 cells assessed as change in body weight at 10 mg/kg, po bid for 10 days relative to control	Mus musculus	2	ALA4834457	organism-based format	Scientific Literature
13.	ALA4836464	Toxicity	Toxicity in mouse transplanted with mouse KIF5B-RET Ba/F3 cells assessed as change in body weight at 20 mg/kg, po bid for 10 days relative to control	Mus musculus	1	ALA4834457	organism-based format	Scientific Literature
14.	ALA4836465	Binding	Inhibition of JAK2 (unknown origin)	Homo sapiens	2	ALA4834457	single protein format	Scientific Literature
15.	ALA4836466	Binding	Inhibition of FLT3 (unknown origin)	Homo sapiens	2	ALA4834457	single protein format	Scientific Literature
16.	ALA4836467	ADME	Intrinsic clearance in human liver microsomes	Homo sapiens	5	ALA4834457	microsome format	Scientific Literature
17.	ALA4836468	ADME	Drug level in plasma of mouse transplanted with mouse KIF5B-RET Ba/F3 cells at 10 mg/kg, po qd for 10 days measured after 8.5 hrs	Mus musculus	2	ALA4834457	organism-based format	Scientific Literature
18.	ALA4836469	ADME	Drug level in tumor of mouse transplanted with mouse KIF5B-RET Ba/F3 cells at 10 mg/kg, po qd for 10 days measured after 8.5 hrs	Mus musculus	2	ALA4834457	organism-based format	Scientific Literature