# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4831257 | B | Inhibition of N-terminal His6-tagged human p70S6k T412E mutant (1 to 421 residues) expressed in Sf21 cells using FITC-AHA-AKRRRLSSLRA-OH as substrate incubated for 90 mins by mobility shift assay | Homo sapiens | 48 | ALA4828767 | cell-based format | Scientific Literature | |
2. | ALA4831258 | B | Inhibition of His-tagged human AKT1 expressed in baculovirus expression system using TC-AHA-GRPRTSSFAEG-NH2 as substrate incubated for 90 mins by mobility shift assay | Homo sapiens | 18 | ALA4828767 | assay format | Scientific Literature | |
3. | ALA4831259 | B | Inhibition of PI3K/Akt/mTOR pathway in human MDA-MB-468 cells assessed as reduction in S6 phosphorylation incubated for 15 to 20 mins by Alexa Fluor 488 staining based assay | Homo sapiens | 18 | ALA4828767 | cell-based format | Scientific Literature | |
4. | ALA4831260 | B | Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP (803 to 918 residues) in baculovirus infected Sf21 cells incubated for 90 mins by mobility shift assay | Homo sapiens | 15 | ALA4828767 | cell-based format | Scientific Literature | |
5. | ALA4831275 | B | Selectivity ratio of IC50 for GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP (803 to 918 residues) in baculovirus infected Sf21 cells to N-terminal His6-tagged human p70S6k T412E mutant (1 to 421 residues) expressed in Sf21 cells | Homo sapiens | 11 | ALA4828767 | cell-based format | Scientific Literature |