The store will not work correctly when cookies are disabled.
JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.
The page will load shortly, Thanks for your patience!
# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4822425 B Inhibition of recombinant human GST-tagged Axl incubated for 1 hr by ADP-glo based luminometry analysis Homo sapiens 21 ALA4819114 single protein format Scientific Literature 2. ALA4822426 B Inhibition of recombinant human GST-tagged Mer using biotinylated peptide as substrate incubated for 1 hr by TR-FRET analysis Homo sapiens 21 ALA4819114 single protein format Scientific Literature 3. ALA4822427 B Inhibition of recombinant human Axl expressed in mouse BaF3 cells assessed as reduction in cell viability incubated for 2 days by cell titer glo assay Homo sapiens 17 ALA4819114 cell-based format Scientific Literature 4. ALA4822428 B Inhibition of recombinant human Mer expressed in mouse BaF3 cells assessed as reduction in cell viability incubated for 2 days by cell titer glo assay Homo sapiens 17 ALA4819114 cell-based format Scientific Literature 5. ALA4822429 P Kinetic solubility of compound in PBS buffer at pH 7 incubated for 15 mins by HPLC-UV analysis 21 ALA4819114 small-molecule physicochemical format Scientific Literature 6. ALA4822430 A Metabolic stability in mouse liver microsomes assessed as residual ratio measured after 30 mins in presence of NADPH by LC-MS/MS analysis relative to absence of NADPH Mus musculus 21 ALA4819114 microsome format Scientific Literature 7. ALA4822431 B Selectivity index, ratio of IC50 for inhibition of recombinant human GST-tagged Mer to IC50 for inhibition of recombinant human GST-tagged Axl Homo sapiens 10 ALA4819114 assay format Scientific Literature 8. ALA4822432 T Toxicity in BALB/c mouse assessed as effect on body weight at 100 mg/kg, po administered for 14 days Mus musculus 2 ALA4819114 organism-based format Scientific Literature 9. ALA4822433 T Toxicity in BALB/c mouse assessed as induction of necrosis in photoreceptor cells at 100 mg/kg, po administered for 14 days hematoxylin and eosin staining based assay Mus musculus 2 ALA4819114 organism-based format Scientific Literature 10. ALA4822434 B Inhibition of Tyro3 (unknown origin) Homo sapiens 2 ALA4819114 single protein format Scientific Literature 11. ALA4822435 B Inhibition of c-Met (unknown origin) Homo sapiens 2 ALA4819114 single protein format Scientific Literature 12. ALA4822436 B Inhibition of LCK (unknown origin) Homo sapiens 2 ALA4819114 single protein format Scientific Literature 13. ALA4822437 A Cmax in CAnN.Cg-Foxnlnu/Cr1Crlj mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Mus musculus 1 ALA4819114 organism-based format Scientific Literature 14. ALA4822438 A Tmax in CAnN.Cg-Foxnlnu/Cr1Crlj mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Mus musculus 1 ALA4819114 organism-based format Scientific Literature 15. ALA4822439 A AUC (0 to 24 hrs) in CAnN.Cg-Foxnlnu/Cr1Crlj mouse at 10 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Mus musculus 1 ALA4819114 organism-based format Scientific Literature 16. ALA4822440 A Cmax in CAnN.Cg-Foxnlnu/Cr1Crlj mouse at 30 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Mus musculus 1 ALA4819114 organism-based format Scientific Literature 17. ALA4822441 A Tmax in CAnN.Cg-Foxnlnu/Cr1Crlj mouse at 30 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Mus musculus 1 ALA4819114 organism-based format Scientific Literature 18. ALA4822442 A AUC (0 to 24 hrs) in CAnN.Cg-Foxnlnu/Cr1Crlj mouse at 30 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Mus musculus 1 ALA4819114 organism-based format Scientific Literature 19. ALA4822443 A Cmax in CAnN.Cg-Foxnlnu/Cr1Crlj mouse at 100 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Mus musculus 1 ALA4819114 organism-based format Scientific Literature 20. ALA4822444 A Tmax in CAnN.Cg-Foxnlnu/Cr1Crlj mouse at 100 mg/kg, po measured upto 24 hrs by LC-MS/MS analysis Mus musculus 1 ALA4819114 organism-based format Scientific Literature