# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4819503 | B | Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells at 10 uM stimulated with ML-SA1 for 200 secs followed by incubation for 200 secs with compound and measured by Fura-2AM dye based single cell Calcium imaging assay | Homo sapiens | 15 | ALA4818989 | cell-based format | Scientific Literature | |
2. | ALA4819507 | B | Inhibition of human TRPML1deltaNC-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis | Homo sapiens | 15 | ALA4818989 | cell-based format | Scientific Literature | |
3. | ALA4819509 | B | Inhibition of human TRPML2-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis | Homo sapiens | 15 | ALA4818989 | cell-based format | Scientific Literature | |
4. | ALA4819510 | B | Inhibition of human TRPML3-YFP expressed in HEK293 cells preincubated for 10 mins followed by stimulation with ML-SA1 and measured after 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis | Homo sapiens | 15 | ALA4818989 | cell-based format | Scientific Literature | |
5. | ALA4819511 | B | Activation of human TRPML1deltaNC-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis | Homo sapiens | 15 | ALA4818989 | cell-based format | Scientific Literature | |
6. | ALA4819512 | B | Activation of human TRPML2-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis | Homo sapiens | 15 | ALA4818989 | cell-based format | Scientific Literature | |
7. | ALA4819513 | B | Activation of human TRPML3-YFP expressed in HEK293 cells incubated for 10 mins by Fluo-4 dye calcium imaging based FLIPR analysis | Homo sapiens | 15 | ALA4818989 | cell-based format | Scientific Literature | |
8. | ALA4819514 | B | Inhibition of human TRPML3-YFP expressed in HEK293 cells at 10 uM stimulated with ML-SA1 for 200 secs followed by incubation for 200 secs with compound and measured by Fura-2AM dye based single cell Calcium imaging assay | Homo sapiens | 3 | ALA4818989 | cell-based format | Scientific Literature |