# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4830153 | Binding | Inhibition of full-length human N-terminal MAHHHHHH tagged-ERK2 expressed in Escherichia coli BL21 (DE3) using ATF2-GFP as substrate incubated for 30 mins in presence of ATP by TR-FRET assay | Homo sapiens | 18 | ALA4828736 | assay format | Scientific Literature | |
2. | ALA4830154 | Functional | Antiproliferative activity against human A-375 cells assessed as reduction in cell viability after 96 hrs by alamar blue assay | Homo sapiens | 23 | ALA4828736 | cell-based format | Scientific Literature | |
3. | ALA4830156 | ADME | Metabolic stability in CD1 mouse liver microsomes assessed as half life at 1 uM measured upto 40 mins in presence of NADPH and UDPGA | Mus musculus | 16 | ALA4828736 | microsome format | Scientific Literature | |
4. | ALA4830157 | ADME | Metabolic stability in human liver microsomes assessed as half life at 1 uM measured upto 40 mins in presence of NADPH and UDPGA | Homo sapiens | 23 | ALA4828736 | microsome format | Scientific Literature |