| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4817964 | Functional | Cytotoxicity against human A673 cells assessed as reduction in cell viability incubated for 48 hrs by cell titer glo assay | Homo sapiens | 11 | ALA4814030 | cell-based format | Scientific Literature | |
| 2. | ALA4817965 | Binding | Inhibition of recombinant human LDHA using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measured after 20 mins by fluorescence based assay | Homo sapiens | 38 | ALA4814030 | single protein format | Scientific Literature | |
| 3. | ALA4817966 | Binding | Inhibition of LDHA in human MIA PaCa2 cells assessed as reduction in lactate production incubated for 2 hrs by fluorescence based assay | Homo sapiens | 38 | ALA4814030 | cell-based format | Scientific Literature | |
| 4. | ALA4817967 | Binding | Inhibition of recombinant human LDHB using sodium pyruvate as substrate preincubated for 5 mins followed by diaphorase/resazurin addition and measured after 20 mins by fluorescence based assay | Homo sapiens | 11 | ALA4814030 | single protein format | Scientific Literature | |
| 5. | ALA4817968 | Functional | Cytotoxicity against human MIA PaCa-2 cells assessed as reduction in cell viability incubated for 48 hrs by cell titer glo assay | Homo sapiens | 11 | ALA4814030 | cell-based format | Scientific Literature | |
| 6. | ALA4817969 | Binding | Inhibition of LDHA in human A673 cells assessed as reduction in lactate production incubated for 2 hrs by fluorescence based assay | Homo sapiens | 11 | ALA4814030 | cell-based format | Scientific Literature | |
| 7. | ALA4817970 | Binding | Binding affinity to LDHA (unknown origin) by SPR analysis | Homo sapiens | 8 | ALA4814030 | single protein format | Scientific Literature | |
| 8. | ALA4817971 | ADME | Metabolic stability in rat microsomes assessed as half life | Rattus norvegicus | 11 | ALA4814030 | microsome format | Scientific Literature | |
| 9. | ALA4817972 | ADME | Permeability of compound by PAMPA | 11 | ALA4814030 | assay format | Scientific Literature | ||
| 10. | ALA4817973 | Physicochemical | Kinetic solubility of compound | 11 | ALA4814030 | small-molecule physicochemical format | Scientific Literature |
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