| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4825605 | B | Displacement of [3H]-gabapentin from human Cav alpha2delta1 expressed in CHO-K1 cell membranes incubated for 60 mins by scintillation counting method | Homo sapiens | 37 | cell membrane format | Scientific Literature | ||
| 2. | ALA4825607 | A | Inhibition of recombinant CYP3A4 (unknown origin) using BFC as substrate at 1 uM measured after 30 mins in presence of NADPH generating system by fluorescence assay relative to control | Homo sapiens | 37 | single protein format | Scientific Literature | ||
| 3. | ALA4825620 | P | Lipophilicity, logP of compound | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 4. | ALA4825621 | P | Lipophilicity, logD of compound at pH 7.4 | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA4825622 | A | Inhibition of CYP1A2 (unknown origin) at 1 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA4825623 | A | Inhibition of CYP2C9 (unknown origin) at 1 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA4825624 | A | Inhibition of CYP2C19 (unknown origin) at 1 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA4825625 | A | Inhibition of CYP2D6 (unknown origin) at 1 uM relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA4825626 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance per mg protein at 1 uM measured upto 60 mins in presence of NADPH generating system by UPLC-MS/MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
| 10. | ALA4825627 | A | Metabolic stability in rat liver microsomes assessed as intrinsic clearance per mg protein at 1 uM measured upto 60 mins in presence of NADPH generating system by UPLC-MS/MS analysis | Rattus norvegicus | 1 | microsome format | Scientific Literature | ||
| 11. | ALA4825628 | A | Metabolic stability in mouse liver microsomes assessed as intrinsic clearance per mg protein at 1 uM measured upto 60 mins in presence of NADPH generating system by UPLC-MS/MS analysis | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 12. | ALA4825629 | B | Inhibition of human ERG | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4825630 | A | Permeability of compound in human Caco2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4825631 | A | Efflux ratio of permeability in human Caco2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4825632 | F | Analgesic activity in CD1 mouse model of capsaicin-induced mechanical hypersensitivity assessed as reduction in mechanical hypersensitivity at 20 mg/kg, ip administered 30 mins prior to capsaicin stimulation and measured after 15 mins | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA4825633 | A | Cmax in CD1 mouse at 20 mg/kg, ip measured upto 24 hrs by UPLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4825634 | A | AUC(0 to t) in CD1 mouse at 20 mg/kg, ip measured upto 24 hrs by UPLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4825635 | A | Induction of motor coordination impairment in CD1 mouse assessed as latency to fall at 20 mg/kg, ip measured upto 180 mins by rotarod test | Mus musculus | 2 | organism-based format | Scientific Literature |
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